Protein Alignment CrebB and CREM

DIOPT Version :9

• Sequence 1: NP_001334685.1
• Gene: CrebB / 32817
• FlyBaseID: FBgn0265784
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: XP_024303592.1
• Gene: CREM / 1390
• HGNCID: 2352
• Length: 360
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 107/350 - (30%)
• Similarity: 143/350 - (40%)
• Gaps: 120/350 - (34%)

  Fly    88 QYPIQTL-AQHGLQVQSVIQANPSGVIQTAAGTQQQQQALAAATAMQKVVYVA------KPPNST 145
            |..::|: :||...:.:.:..:.|..:||..| |....|||.       |.||      ..|..|
Human    16 QMTMETVESQHDGSITASLTESKSAHVQTQTG-QNSIPALAQ-------VSVAGSGTRRGSPAVT 72

  Fly   146 VIHTTPGNAVQVRNKIPPTFPCKIK-PEPNTQHP---EDSDESLSDD---DSQHHRSELTRRPSY 203
            ::....|..:.|:..|....|..|: .|.:|...   .::|||...:   ||...|..|:|||||
Human    73 LVQLPSGQTIHVQGVIQTPQPWVIQSSEIHTVQVAAIAETDESAESEGVIDSHKRREILSRRPSY 137

  Fly   204 NKIFTEISGPDMSGA---------------------------------------------SLPMS 223
            .||..|:|. |:.|.                                             |.|.|
Human   138 RKILNELSS-DVPGVPKIEEERSEEEGTPPSIATMAVPTSIYQTSTGQYIAIAQGGTIQISNPGS 201

  Fly   224 DGVLNSQ-LAGTGAGGNAANSSLMQL----------------------DPTYYLSNRMSYNTNN- 264
            |||...| |..|.:|.....::::|.                      :.|....:.|:..|.:
Human   202 DGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETELAPSHMAAATGDM 266

  Fly   265 ----------------------------SGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLE 301
                                        ..:||:.|||||:||.||||||||||||||||:||||
Human   267 PTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAARECRRKKKEYVKCLE 331

  Fly   302 NRVAVLENQNKALIEELKSLKELYC 326
            |||||||||||.||||||:||:|||
Human   332 NRVAVLENQNKTLIEELKALKDLYC 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrebB	NP_001334685.1	None
CREM	XP_024303592.1	pKID	117..154	CDD:308015	15/37 (41%)
		bZIP_CREB1	304..358	CDD:269838	46/52 (88%)
		coiled coil	305..357	CDD:269838	45/51 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144434
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I4360
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D407205at33208
OrthoFinder	1	1.000	-	-		FOG0001658
OrthoInspector	1	1.000	-	-		otm40992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45879
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1385
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	8.090