DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6106 and Dpysl5

DIOPT Version :9

Sequence 1:	NP_001285403.1	Gene:	CG6106 / 32816	FlyBaseID:	FBgn0030914	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_075412.1	Gene:	Dpysl5 / 65208	RGDID:	620467	Length:	564	Species:	Rattus norvegicus

Alignment Length:	518	Identity:	126/518 - (24%)
Similarity:	198/518 - (38%)	Gaps:	86/518 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SQNALIHGGIIVDTE-----------GIIRRVLRSPQEVNTYLYNTESESVYDFGDLVLMPGLID 69
            |...||.||.:|:.:           |||       |:|...|.......|.|....:::||.||
  Rat     7 SVRILIKGGKVVNDDCTHEADVYIENGII-------QQVGRELMIPGGAKVIDATGKLVIPGGID 64

  Fly    70 PNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKAKTSTARGKI---- 128
            .:.|.::.  .....:.|...||||..||.|.||......:..::..|:.|.: :.|..|:
  Rat    65 TSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCR-ALADPKVCCDY 128

  Fly   129 --YVDVGFWGGLVPGNGDQLAALLGAGVMGLQCTLCD----PAAPVSQEFPAVNESQLEEALSQL 187
              :|.:.:|...|....:.|....|.....:..|..|    ..:.:.|.|.|..:      ...:
  Rat   129 ALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVFHACRD------FGAI 187

  Fly   188 DKDQAEGEAIVAVHAELPLTTEIHPDEEAPREYGTFLVTRPPQMEISATQLLCRLANRHPRRC-I 251
            .:..||...:||..|:..|...|...|...       ::.|.::|..||..:..:|||  ..| |
  Rat   188 PRVHAENGELVAEGAKEALDLGITGPEGIE-------ISHPEELEAEATHRVITIANR--THCPI 243

  Fly   252 HILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAA-----EDVPDCGTEFKTWPPIRERRNQE 311
            :::|.||..:..::...:.||..:..:|...:..|..     :|...... :.|.||:|...|..
  Rat   244 YLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAA-YVTVPPLRLDTNTS 307

  Fly   312 QLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQLSLSVVWTAAANRRG- 375
            ....:|.....:.::.|||.|.|...:|:    |:.:|.|...|::.:|..:||||     .||
  Rat   308 TYLMSLLANDTLNIVASDHRPFTTKQKAM----GKEDFTKIPHGVSGVQDRMSVVW-----ERGV 363

  Fly   376 -----SANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTVGPELLYTATKA 435
                 ..|..:|    :.....|.:..|...||||..|.|||..||.||...|:...........
  Rat   364 VGGKMDENRFVA----VTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDF 424

  Fly   436 TPYAGQKLRGVVHATVVRGLHVYQQ-----FEGFGQ--PLG-------KVLLRRSSRKLVKFV 484
            ..|...:..||...|:.||..||:.     .||.|:  ||.       |.|::|.....|:.|
  Rat   425 NLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRGV 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	122/505 (24%)
Dpysl5	NP_075412.1	D-HYD	10..459	CDD:238639	117/485 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820