DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6106 and dpysl4

DIOPT Version :9

Sequence 1:	NP_001285403.1	Gene:	CG6106 / 32816	FlyBaseID:	FBgn0030914	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_021335783.1	Gene:	dpysl4 / 553411	ZFINID:	ZDB-GENE-050720-3	Length:	675	Species:	Danio rerio

Alignment Length:	508	Identity:	114/508 - (22%)
Similarity:	195/508 - (38%)	Gaps:	111/508 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SQNALIHGGIIVD-----------TEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLVLMPG 66
            |...:|.||.||:           .:|||:::   |..|..|.|         |..:|.:|: ||
Zfish   115 SDKLIIKGGKIVNDDQSFYADIYVEDGIIKQIGENLIVPTGVKT---------VDAYGHIVI-PG 169

  Fly    67 LIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKA---------K 120
            .||.|..:..|  |....:.|...|:||.|||.|.|||...    |....:.|.|         |
Zfish   170 GIDVNTCLQAPHLGMSPADDFYHGTRAALAGGTTMIIDHVV----PEPGSSLLSAFDQWKDTADK 230

  Fly   121 TSTARGKIYVDVGFW-GGLVPGNGDQLAALL-GAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEA 183
            .|.....:::|:..| .||.    ::|.:|: ..||......:.     ...:|.: :::|:.|.
Zfish   231 RSCCDYSLHIDITRWHDGLF----EELESLVKDKGVNSFLIFMA-----YKDKFQS-SDTQIYEM 285

  Fly   184 LSQLDKDQAEGEAIVAVHAELPLTTEIHPDEE---------APREYGTFLVTRPPQMEISATQLL 239
            .|.:    .|..||..||||   ..:|..:|:         .|..:   :::.|.::|..|....
Zfish   286 FSAM----RELGAIAQVHAE---NGDIIEEEQKKLLDLGITGPEGH---VLSHPEEVETEAVYRA 340

  Fly   240 CRLANRHPRRC-IHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDV-PDCGTE----- 297
            ..:|.:  ..| ::|....|..:..|:.:.|::|           :.:..|.: ...||:
Zfish   341 ITIAKQ--ANCPLYITKVMSKPAADLIAKARKKG-----------MVIYGEPIAASLGTDGSHYW 392

  Fly   298 FKTW---------PPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAW 353
            .|.|         ||:....:......:|...|.:::..|.:...|...:|:    |:.:|....
Zfish   393 SKNWAEAAAFVMSPPLNPDTSTPDYLNSLLSCGDLQVTASANCTFTTAQKAV----GKDDFTFIP 453

  Fly   354 PGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSP 418
            .|.|.::..:|:||..|.   .:..:...|...:.....|.:..|...|||||.|.|||..:|:.
Zfish   454 EGTNGIEERMSIVWDKAV---ATGKMDENDFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWNT 515

  Fly   419 EEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQ-----FEGFGQ 466
            :|..|...:......:...:.|.:.||.....:.:|..|.:.     .||.|:
Zfish   516 KETRTFSAKTHNLTVEVNIFEGMECRGFPVLVISQGRIVLEDGTLSVMEGSGR 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	114/508 (22%)
dpysl4	XP_021335783.1	D-HYD	118..567	CDD:238639	112/502 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920