DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6106 and dpysl3

DIOPT Version :9

Sequence 1:	NP_001285403.1	Gene:	CG6106 / 32816	FlyBaseID:	FBgn0030914	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001018348.1	Gene:	dpysl3 / 553166	ZFINID:	ZDB-GENE-050720-2	Length:	567	Species:	Danio rerio

Alignment Length:	485	Identity:	114/485 - (23%)
Similarity:	195/485 - (40%)	Gaps:	94/485 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SQNALIHGGIIVD-----------TEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLVLMPG 66
            |:..||.||.||:           .:|:|:::   |..|..|.|...|         |.:|: ||
Zfish    14 SERLLIKGGRIVNDDQSFYADIYMEDGVIKQIGDNLIVPGGVKTIEAN---------GKMVI-PG 68

  Fly    67 LIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKA---------K 120
            .||.:.|:..|  |....:.|...||||.|||.|.|:|...    |....:.|:|         :
Zfish    69 GIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVI----PEPGCSLLEAFDRWSKWADE 129

  Fly   121 TSTARGKIYVDVGFWGGLVPGNGDQLAALLGAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEALS 185
            .:.....::||:..|...|....:.|  :...||...|..:      ..::...::.::|.|..:
Zfish   130 KACCDYSLHVDITHWNDSVKQEVETL--IKEKGVNSFQVYM------AFKDLYQMSNTELYEVFT 186

  Fly   186 QLDKDQAEGEAIVAVHAELPLTTEIHPDEEAPR-EYGT-----FLVTRPPQMEISATQLLCRLAN 244
            .|    .|...|..||||   ..||..:|:|.. |.|.     .:::||.::|..|......:|:
Zfish   187 FL----GEHGGIAQVHAE---NGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIAS 244

  Fly   245 RHPRRC-IHILNCSSGESLPLVEECRRQG---------GNLTVDTCPHY----LALAAEDVPDCG 295
            :  ..| :::....|..:..::.:.|::|         .:|..|. .||    .|.||
Zfish   245 Q--TNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDG-THYWSKNWAKAA------- 299

  Fly   296 TEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQ 360
             .|.|.||:............|...|.:.::||.|...:...:|:    |:.:|.:...|:|..:
Zfish   300 -SFVTSPPLSPDPTTPDYLNTLLASGDLSVVGSAHCTFSVAQKAI----GKDDFTQIPEGVNGAE 359

  Fly   361 LSLSVVW-TAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTV 424
            ..:|::| .|....:...|:.:|    :.....|.:..|...|||||.|.|:|..:|..:...|:
Zfish   360 ERMSIIWDKAVVTGKMDENMFVA----VTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTI 420

  Fly   425 GPELLYTATKATPYAGQKLRGVVHATVVRG 454
            ..:..::|.:...:.|.:|||.....|.:|
Zfish   421 TAKTHHSAAEYNVFEGMELRGAPMLVVCQG 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	114/485 (24%)
dpysl3	NP_001018348.1	PRK09060	17..467	CDD:181632	113/482 (23%)
		D-HYD	17..466	CDD:238639	113/482 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	505..567
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920