Protein Alignment CG6106 and DPYSL3

DIOPT Version :9

• Sequence 1: NP_001285403.1
• Gene: CG6106 / 32816
• FlyBaseID: FBgn0030914
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001184223.1
• Gene: DPYSL3 / 1809
• HGNCID: 3015
• Length: 684
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 131/527 - (24%)
• Similarity: 210/527 - (39%)
• Gaps: 110/527 - (20%)

  Fly    14 DGSQNALIHGGIIVD-----------TEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLVLM 64
            |.|...||.||.||:           .:|:|:::   |..|..|.|...|         |.:|:
Human   126 DKSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEAN---------GKMVI- 180

  Fly    65 PGLIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKAKTSTARGK 127
            ||.||.:.|...|  |....:.|...||||.|||.|.|||........:::.|:.|.: ..|.||
Human   181 PGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWR-EWADGK 244

  Fly   128 ------IYVDVGFWGGLVPGNGDQLAALLGAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEALSQ 186
                  ::||:..|...|......|  :...||......:      ..::...|:.::|.|..:.
Human   245 SCCDYALHVDITHWNDSVKQEVQNL--IKDKGVNSFMVYM------AYKDLYQVSNTELYEIFTC 301

  Fly   187 LDKDQAEGE--AIVAVHAELPLTTEIHPDEEAPR-EYGT-----FLVTRPPQMEISATQLLCRLA 243
            |      ||  ||..||||   ..:|...|:... |.|.     .:::||.::|..|......:|
Human   302 L------GELGAIAQVHAE---NGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIA 357

  Fly   244 NRHPRRC-IHILNCSSGESLPLVEECRRQG---------GNLTVDTCPHY----LALAAEDVPDC 294
            ::  ..| :::....|..:..|:.:.|::|         .:|.:|. .||    .|.||
Human   358 SQ--TNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDG-THYWSKNWAKAA------ 413

  Fly   295 GTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSL 359
              .|.|.||:...........:|...|.:::.||.|...:...:|:    |:.||.....|.|.:
Human   414 --AFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAI----GKDNFTAIPEGTNGV 472

  Fly   360 QLSLSVVW-TAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFT 423
            :..:||:| .|.|..:...|..:|    :.....|.:..|...||||:.|.|:|..:|.|:....
Human   473 EERMSVIWDKAVATGKMDENQFVA----VTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKI 533

  Fly   424 VGPELLYTATKATPYAGQKLRGVVHATVVRG--------LHVYQQFEGFGQ-----PLGKVLLRR 475
            |..:...:|.:...:.|.:|||.....:.:|        |||.|   |.|:     |....:.:|
Human   534 VSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQ---GAGRFIPCSPFSDYVYKR 595

  Fly   476 --SSRKL 480
              :.||:
Human   596 IKARRKM 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	128/516 (25%)
DPYSL3	NP_001184223.1	D-hydantoinase	131..585	CDD:273937	125/503 (25%)
		VOC	574..679	CDD:387367	9/32 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820