Protein Alignment CG6106 and unc-33

DIOPT Version :9

• Sequence 1: NP_001285403.1
• Gene: CG6106 / 32816
• FlyBaseID: FBgn0030914
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001033438.1
• Gene: unc-33 / 177112
• WormBaseID: WBGene00006769
• Length: 854
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 115/516 - (22%)
• Similarity: 181/516 - (35%)
• Gaps: 112/516 - (21%)

  Fly     1 MDLLFLSRRIFLGDGSQNALIHGGIIVDTEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLV 62
            |.:|.:.....:.|   :|:....|::: :|||:.|   |.:|          |...|.|....:
 Worm   332 MSILLVKNAQIVND---DAIFVADILIE-DGIIQNVAPNLEAP----------EGAEVLDAAGKL 382

  Fly    63 LMPGLIDPNVHINEPGRKDWEGFATATKAAAAGGFTTIID--RPTNAQPPTVSVAHLKAKTSTAR 125
            .:|..||....:.:....|   .:|..|:|.|||..||::  ||..|:....:|..:|.:...:.
 Worm   383 ALPAGIDVYTQVTDSSVDD---LSTGCKSAIAGGTGTIVEVVRPRGAESVVSAVKRVKNQLEKSG 444

  Fly   126 GKIYVDVGF---------WGGLVPGNGDQLAALLGAGVMGLQCTLCDPAAPVSQEFPAVNESQLE 181
            ...:|.:..         ...||...|.....|.|..:                    .::..||
 Worm   445 ISCHVALSVAITDFCEQEMSELVKNEGINSFVLDGVSL--------------------TDDKLLE 489

  Fly   182 -----EALSQLDKDQAEGEAIVAVHAELPLTTEIHPDEEAPREYGTFLVTRPPQMEISATQLLCR 241
                 :.|..|.:...|.::|||:..:..|...:...|..|:       :||..:|......:|.
 Worm   490 LFEHVKRLGALIRVVPENKSIVAMLEKKMLKLGVTGPEGFPQ-------SRPESLEADRVSGVCV 547

  Fly   242 LANRHPRRC-IHILNCSSGESLPLVEECRRQG---------GNLTVDTCPHYLALAAEDVPDCGT 296
            |.|.  ..| |.|:..||.:||..:|:.|..|         ..:|.|..    ||.::|:.....
 Worm   548 LGNL--ASCPISIVQVSSADSLAAIEKARASGALAHAEIASAAVTADGS----ALFSQDLRFASA 606

  Fly   297 EFKTWPPIRERRNQEQLWQALRPGGAIRMIG-----------SDHSPATPGARALTCGRGRGNFL 350
            .....|              ||.|...||||           |.|.|.....|.     ...:|.
 Worm   607 HLTDVP--------------LRRGAPDRMIGALSTQPLVVCTSGHRPVNSATRV-----AAKDFA 652

  Fly   351 KAWPGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCV 415
            .|..|....:..::|||..|..   |..:.......:.....|.:..:...|||||.|.|||..:
 Worm   653 IAQKGSTGAEERMAVVWERAVR---SGRIDAMRFVAVTSTNAAKMFNMYPKKGRIAVGADADLVI 714

  Fly   416 WSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQFEGFGQPLGKVLLRRS 476
            |....:..:......::.:.:.|.|..:..||.||:|.|...||..|....|:....||.|
 Worm   715 WDASGKRVLESSRAQSSQENSMYDGLTVHSVVTATIVGGKIAYQNGEVREAPVAGGFLRLS 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	111/510 (22%)
unc-33	NP_001033438.1	metallo-dependent_hydrolases	335..769	CDD:381920	111/505 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.917438	Normalized mean entropy	S1869
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101673
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770