Protein Alignment CG6106 and DPYSL4

DIOPT Version :9

• Sequence 1: NP_001285403.1
• Gene: CG6106 / 32816
• FlyBaseID: FBgn0030914
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_006417.2
• Gene: DPYSL4 / 10570
• HGNCID: 3016
• Length: 572
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 116/520 - (22%)
• Similarity: 195/520 - (37%)
• Gaps: 119/520 - (22%)

  Fly    16 SQNALIHGGIIVD-----------TEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLVLMPG 66
            |...||.||.||:           .:|:|:::   |..|..:.|          .|...|:::||
Human    14 SDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGGIKT----------IDAHGLMVLPG 68

  Fly    67 LIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKA---------K 120
            .:|.:..:..|  |....:.|...||||.|||.|.|:|...    |...|:.|.|         .
Human    69 GVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVF----PDTGVSLLAAYEQWRERADS 129

  Fly   121 TSTARGKIYVDVGFWGGLVPGNGDQLAALL-GAGVMGL----------QCTLCDPAAPVSQEFPA 174
            .:.....::||:..|...:.   ::|.||: ..||...          ||
Human   130 AACCDYSLHVDITRWHESIK---EELEALVKEKGVNSFLVFMAYKDRCQC--------------- 176

  Fly   175 VNESQLEEALSQLDKDQAEGEAIVAVHAELPLTTEIHPDEEAPR--EYGT-----FLVTRPPQME 232
             ::||:.|..| :.:|..   |:..||||.....|    ||..|  |.|.     .:::.|.::|
Human   177 -SDSQMYEIFS-IIRDLG---ALAQVHAENGDIVE----EEQKRLLELGITGPEGHVLSHPEEVE 232

  Fly   233 ISATQLLCRLANRHPRRC-IHILNCSSGESLPLVEECRRQG---------GNLTVDTCPHY---- 283
            ..|......:|.:  ..| :::....|..:...:.:.:|:|         .:|..|. .||
Human   233 AEAVYRAVTIAKQ--ANCPLYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDG-SHYWSKN 294

  Fly   284 LALAAEDVPDCGTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGN 348
            .|.||        .|.|.||:............|...|.:::.||.|...|...:|:    |:.|
Human   295 WAKAA--------AFVTSPPVNPDPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAV----GKDN 347

  Fly   349 FLKAWPGINSLQLSLSVVW-TAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDAD 412
            |.....|.|.::..:|:|| ...|:.:...|..:|    :.....|.:......|||:|.|.|||
Human   348 FALIPEGTNGIEERMSMVWEKCVASGKMDENEFVA----VTSTNAAKIFNFYPRKGRVAVGSDAD 408

  Fly   413 FCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQFEGFGQP-LGKVLLRRS 476
            ..:|:|:....:..:......:...:.|.:.||.....:.:|....:..:.|..| .|:.:.|::
Human   409 LVIWNPKATKIISAKTHNLNVEYNIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKT 473

  Fly   477  476
            Human   474  473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	115/515 (22%)
DPYSL4	NP_006417.2	D-HYD	17..466	CDD:238639	113/508 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820