Protein Alignment upd1 and upd2

DIOPT Version :10

• Sequence 1: NP_525095.2
• Gene: upd1 / 32813
• FlyBaseID: FBgn0004956
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001356882.1
• Gene: upd2 / 32805
• FlyBaseID: FBgn0030904
• Length: 406
• Species: Drosophila melanogaster
• Alignment Length: 443
• Identity: 122/443 - (27%)
• Similarity: 189/443 - (42%)
• Gaps: 114/443 - (25%)

  Fly     2 ARPLLLLLPILLVLLLAAQLPHLAE-------------GR------STTSSGG--LTVIDSERLR 45
            :|.:||::.||.|::...:..||.:             ||      |::||||  |...|....|
  Fly    29 SRQVLLVIMILSVVMPFTKARHLRDQVALDYAYDEDNSGRSSSSSSSSSSSGGDILPAFDVNPYR 93

  Fly    46 IRTTS------------STASAQHPNQGTIPASAASPRKRHRKRNSNWIDYRNFDENTTALEWAN 98
            ....|            |.:|.:...|..|.| |....:|.|.|::...:.|.|...:...||.|
  Fly    94 GLADSFGEGSYDSDMSLSESSYEEIAQAAIRA-ARREMRRQRTRHARSHNLRLFSGKSEIPEWEN 157

  Fly    99 PCGGNYHP--SAGDRF---NRQRPRQSFNQLKRHAFREYRSLNSSQDSAIDIRNMTMWSLHTHNY 158
            ||||.|.|  |..|..   .|...|:....|:.....||:.:  :..:.::..|:..|.   ..|
  Fly   158 PCGGTYTPDESLSDSSASQGRVIKRKHLENLRNITMSEYQDI--THRATLEYGNLQHWQ---REY 217

  Fly   159 KFLPKL-KPNSTIALKRWYRNMQTYVASFAYLRRQQ--IRWDQRSITRESSTARELRELLLSSRR 220
            ||||.: :|.|.:.||.|||:|||:|.||:||.|.|  .|.||:....|:.| :||.:||:|:|.
  Fly   218 KFLPNMTRPTSAVKLKTWYRHMQTFVGSFSYLGRAQYKFRKDQQKSLNEAVT-KELHDLLVSARY 281

  Fly   221 ILCELETAVNQTQSPRQKQRRSGAAVTAVGGTTMLGQQLPQISRLEMNKRLKLRSKTSGPGMGGA 285
            :|||:|..:|.:. |...                 |.:|.::||..|.:||...:..:|
  Fly   282 MLCEIELTINASY-PNSN-----------------GAKLSRVSRQAMEERLNFHTPANG------ 322

  Fly   286 ASSASMAAGEADSIDMRFVKHHYYDFLRTMYQLLRRDGKRVRSRPRKHHKKQQR-------SQKK 343
                ||   |||..|::..|..|:.:|..:::.|.    ||..|||::..:::.       ....
  Fly   323 ----SM---EADQRDLKVSKELYFQYLNNVWKTLH----RVLRRPRRNSAERRHLAAIHGTGASG 376

  Fly   344 LLQQQQQLADQLEQRWRSSTLNGKEFNEVSKPVAGGAAGVADVAGVSGGGSNQ 396
            |.....::.|       ..:.||          :||::|       |.||||:
  Fly   377 LRAGSSEMLD-------VGSSNG----------SGGSSG-------SDGGSNE 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
upd1	NP_525095.2	Unpaired	71..232	CDD:374263	61/168 (36%)
upd2	NP_001356882.1	Unpaired	144..293	CDD:374263	58/154 (38%)