Protein Alignment CG33639 and gpr139

DIOPT Version :10

• Sequence 1: NP_001027070.1
• Gene: CG33639 / 32803
• FlyBaseID: FBgn0053639
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001352082.1
• Gene: gpr139 / 798482
• ZFINID: ZDB-GENE-050823-2
• Length: 363
• Species: Danio rerio
• Alignment Length: 440
• Identity: 96/440 - (21%)
• Similarity: 164/440 - (37%)
• Gaps: 161/440 - (36%)

  Fly    29 VLAANATSVFSSDLRDDFYRDVEDPRTESLREYCYGLVLPIICAMGIIGNVLNLVVLTRRNMR-- 91
            ||..|::|              ..||...|.::.......::| :|:..|:|.:::|::..:|
Zfish     9 VLTTNSSS--------------WSPRGCPLGQFPVVYYSSLLC-LGLPANILTVIILSQLVLRRQ 58

  Fly    92 GTAYIYMRAYSTA---ALLAIVFA------------IPFGIRMLVHKDRGQWEEFGPAFYTAHLE 141
            .::|.|:.|.:.|   .||.|||.            :|..:...|     |..||.    :.|..
Zfish    59 KSSYNYLLALAVADILVLLLIVFVDFLLEDFILGAPLPHSLNKAV-----QVLEFS----SIHTS 114

  Fly   142 LYLGNGCLGVGVMMLLVLTIERYVSVCHPGFARPVMGPPG-----VVVFLTCLATVIVYL--PSI 199
            :::           .:.|||:||::||||.....|..|..     :.|:..||.:.:.|.  |.:
Zfish   115 IWI-----------TVPLTIDRYIAVCHPLRYHTVSYPARTRKVILAVYAGCLISSVPYYWWPEL 168

  Fly   200 FRGELIKCILGSSD------------VYVYLRRDNTIYQQTIFYRVYKIMLEVIFKLVPTLVIGG 252
            :.|     :.|:|.            |:|:..   |:|                  |:|..|...
Zfish   169 WHG-----LPGASPGGRSSSAGQHVLVWVHCA---TVY------------------LLPCSVFFS 207

  Fly   253 LNMRIM--MVYRRTCERRRKMVLSRPHAQGHGHGHGHGHGHGHGHAHGHGYLKDDDPRKFAEERR 315
            ||..|:  :..||:|.|.|                        |::.|               :.
Zfish   208 LNAIIVRKLRCRRSCFRLR------------------------GYSTG---------------KT 233

  Fly   316 LFLLLGSTSILFLVCVSPMAILHMTIASEVYPSFP-----FQVFRASANLLELINYSLTFYIYCL 375
            ..:||..||: |.|..:|..::.:.....|.|:.|     ..:....||:|.|:|..:.|::||.
Zfish   234 TAILLAITSV-FAVLWAPRTLMILYHLYTVQPAMPGPARLLHLVTDVANMLALLNTGVNFFLYCF 297

  Fly   376 FSEDFRNTLVRTIKWPWLKGKF-CHQ------AEH--EVSASP---PATA 413
            .|:.||. :..|:    ||..| |.:      |.|  .:::||   ||.:
Zfish   298 ISKRFRR-MAGTV----LKAFFRCRKQPPPFYASHNFSITSSPWISPANS 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33639	NP_001027070.1	7tmA_FMRFamide_R-like	61..384	CDD:410630	78/365 (21%)
		TM helix 1	62..88	CDD:410630	5/25 (20%)
		TM helix 2	94..119	CDD:410630	10/39 (26%)
		TM helix 3	138..168	CDD:410630	6/29 (21%)
		TM helix 4	178..198	CDD:410630	5/26 (19%)
		TM helix 5	231..256	CDD:410630	5/24 (21%)
		TM helix 6	311..339	CDD:410630	7/27 (26%)
		TM helix 7	352..377	CDD:410630	8/24 (33%)
gpr139	NP_001352082.1	7tmA_GPR139	28..306	CDD:320585	78/365 (21%)
		TM helix 1	28..53	CDD:320585	5/25 (20%)
		TM helix 2	61..86	CDD:320585	9/24 (38%)
		TM helix 3	100..130	CDD:320585	10/49 (20%)
		TM helix 4	142..162	CDD:320585	3/19 (16%)
		TM helix 5	186..211	CDD:320585	9/45 (20%)
		TM helix 6	228..260	CDD:320585	8/47 (17%)
		TM helix 7	274..299	CDD:320585	8/24 (33%)