Protein Alignment CG33639 and Gpr139

DIOPT Version :9

• Sequence 1: NP_001027070.1
• Gene: CG33639 / 32803
• FlyBaseID: FBgn0053639
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001019412.1
• Gene: Gpr139 / 293545
• RGDID: 1311729
• Length: 345
• Species: Rattus norvegicus
• Alignment Length: 337
• Identity: 73/337 - (21%)
• Similarity: 136/337 - (40%)
• Gaps: 87/337 - (25%)

  Fly    69 IICAMGIIGNVLNLVVLTR--RNMRGTAYIYMRAYSTAALLAIVFAIPFGIRMLVHKDRGQWEEF 131
            ::| :|:..|:|.:::|::  ...:.::|.|:.|.:.|.:| ::|.|.|...:|        |:|
  Rat    28 LLC-LGLPANILTVIILSQLVARRQKSSYNYLLALAAADIL-VLFFIVFVDFLL--------EDF 82

  Fly   132 -----GPAFYTAHLELYLGNGCLGVGVMMLLVLTIERYVSVCHPGFARPVMGPPG-----VVVFL 186
                 .|......:|: |....:...:.:.:.||::||::||||.....|..|..     :.|::
  Rat    83 ILTMQMPPIPDKIIEV-LEFSSIHTSIWITVPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYI 146

  Fly   187 TCLATVIVYL--PSIFRGELIKCILGSSDVYVYLRRDNTIYQQTIFYRVYKIMLEVIFKLVPTLV 249
            ||..|.|.|.  |:|:..:.|...:....|:::.            :.||         |||..:
  Rat   147 TCFLTSIPYYWWPNIWTEDYISTSMHHVLVWIHC------------FTVY---------LVPCSI 190

  Fly   250 IGGLNMRIMMVYRRTCERRRKMVLSRPHAQGHGHGHGHGHGHGHGHAHGHGYLKDDDPRKFAEER 314
            ...||..|:...||....|.:                       |::.|               :
  Rat   191 FFILNSIIVYKLRRKSNFRLR-----------------------GYSTG---------------K 217

  Fly   315 RLFLLLGSTSILFLVCVSP--MAILHMTIASEVYPSFPFQVFRASANLLELINYSLTFYIYCLFS 377
            ...:|...||| |....:|  :.||:....:.:...:...:....||:|.|:|.::.|::||..|
  Rat   218 TTAILFTITSI-FATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFIS 281

  Fly   378 EDFRNTLVRTIK 389
            :.||.....|:|
  Rat   282 KRFRTMAAATLK 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33639	NP_001027070.1	7tm_1	77..>278	CDD:278431	48/214 (22%)
Gpr139	NP_001019412.1	7tmA_GPR139	19..288	CDD:320585	71/330 (22%)
		TM helix 1	21..45	CDD:320585	5/17 (29%)
		TM helix 2	55..77	CDD:320585	8/22 (36%)
		TM helix 3	94..116	CDD:320585	3/22 (14%)
		TM helix 4	139..155	CDD:320585	5/15 (33%)
		TM helix 5	173..196	CDD:320585	7/43 (16%)
		TM helix 6	219..241	CDD:320585	6/22 (27%)
		TM helix 7	256..281	CDD:320585	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840