DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33639 and C17H11.1

DIOPT Version :9

Sequence 1:	NP_001027070.1	Gene:	CG33639 / 32803	FlyBaseID:	FBgn0053639	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_509379.1	Gene:	C17H11.1 / 181075	WormBaseID:	WBGene00015921	Length:	475	Species:	Caenorhabditis elegans

Alignment Length:	351	Identity:	77/351 - (21%)
Similarity:	158/351 - (45%)	Gaps:	31/351 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DDFYRDVEDPRTESLREY-----CYGLVLPIICAMGIIGNVLNLVVLTRRNMRGTAYIYMRAYST 103
            |.|..:....|.|...|.     .:.::....|.:|:.||:|||..|...:::...::|:::.:.
Worm    29 DSFCMETNGTRAELSPELIKVKDAFTILQVTCCILGVFGNILNLQTLRSPSLQTVPFMYIKSLAI 93

  Fly   104 AALLAIVFAIPFGIRMLVHKDRGQWEEFG-PAFYTAHLELYLGNGCLGVGVMMLLVLTIERYVSV 167
            ..|:|:..       :|:|.......:.. ..:||.::|....||.|..|:....:||:|||..:
Worm    94 FDLIALTM-------ILIHYCLVSTTKMAFVMYYTTYIEAPFINGFLISGLYCSFLLTLERYFLI 151

  Fly   168 CHPGFARPVMGPPGVV---VFLTCLATVIVYLPSIFRGELIKCILGSSDVYVYLRRDNTIYQQT- 228
            ..| ..:|...|....   ::.....:.:::||.:.:..|   .:..:..||.......:.|:.
Worm   152 SRP-HQKPTPFPREQARRRIYTMLALSFLIHLPMVLQRRL---SVNENGEYVIKNNVELLCQEPN 212

  Fly   229 -IFYRVYKIMLEVI-FKLVPTLVIGGLNMRIMMVYRRTCERRRKMVLSRPHAQGHGHGHGHGHGH 291
             ..|..||::.|.: |.:|.::.|  :|:.|....:.|.:|||::|..........:|..   ..
Worm   213 WSLYNYYKLIRECVRFLIVISMTI--INIIIARKLQITKKRRRRLVRRSSPQNEIPNGIS---AD 272

  Fly   292 GHGHAHGHGYLKDDDP--RKFAEERRLFLLLGSTSILFLVCVSPMAILHMTIASEVYPSFPFQVF 354
            ...:.:.....::|..  |.|. |::|.:|:.|..::||:...|..::.:.....:..:|.||::
Worm   273 SESNVNSFTMRREDSNLIRSFT-EKKLTVLMISICVIFLLGNVPQIVVMILQNEAMETNFNFQLY 336

  Fly   355 RASANLLELINYSLTFYIYCLFSEDF 380
            |..:|.||::|:.|.||::|:.|.::
Worm   337 RHCSNTLEVLNHCLNFYVFCIASSEY 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33639	NP_001027070.1	7tm_1	77..>278	CDD:278431	46/207 (22%)
C17H11.1	NP_509379.1	7tmA_FMRFamide_R-like	53..366	CDD:320109	72/327 (22%)
		TM helix 1	53..77	CDD:320109	8/23 (35%)
		TM helix 2	85..107	CDD:320109	5/28 (18%)
		TM helix 3	123..145	CDD:320109	6/21 (29%)
		TM helix 4	168..184	CDD:320109	1/15 (7%)
		TM helix 5	217..239	CDD:320109	6/23 (26%)
		TM helix 6	296..321	CDD:320109	6/24 (25%)
		TM helix 7	334..359	CDD:320109	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0016698
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.970