DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hesr and hey2

DIOPT Version :9

Sequence 1:	NP_525094.1	Gene:	Hesr / 32800	FlyBaseID:	FBgn0030899	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_571697.2	Gene:	hey2 / 58146	ZFINID:	ZDB-GENE-000526-1	Length:	324	Species:	Danio rerio

Alignment Length:	100	Identity:	27/100 - (27%)
Similarity:	48/100 - (48%)	Gaps:	16/100 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 REVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAVHHLSKKNCPVATPT 86
            |:..:.::|::||.|||..|..::.|:.......|.  ||::..::|::.|.||.....
Zfish    49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQA------ 105

  Fly    87 TAPTSG-----VYQSPIDCYWSGFRECVLEVSQFL 116
               |.|     .:...:|....|||||:.||:::|
Zfish   106 ---TGGKGYFDAHSLAMDFLSIGFRECLTEVARYL 137

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hesr	NP_525094.1	HLH	21..77	CDD:238036	16/54 (30%)
Hesr	NP_525094.1	Hairy_orange	101..>116	CDD:295407	7/14 (50%)
hey2	NP_571697.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		HLH	49..105	CDD:238036	16/57 (28%)
		Hairy_orange	125..162	CDD:284859	7/12 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..324
		YRPW motif	314..317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740