Protein Alignment Hesr and HES4

DIOPT Version :9

• Sequence 1: NP_525094.1
• Gene: Hesr / 32800
• FlyBaseID: FBgn0030899
• Length: 149
• Species: Drosophila melanogaster
• Sequence 2: NP_001135939.1
• Gene: HES4 / 57801
• HGNCID: 24149
• Length: 247
• Species: Homo sapiens
• Alignment Length: 122
• Identity: 38/122 - (31%)
• Similarity: 64/122 - (52%)
• Gaps: 10/122 - (8%)

  Fly    26 KPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAVHHL-SKKNCPVATPTTAP 89
            ||:||::||:|||..|..:|.|:.:....:....:|::..|:||:.|.|| |.:...|....:|.
Human    65 KPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSAD 129

  Fly    90 TS--GVYQSPIDCYWSGFRECVLEVSQFLQHNGYQPSFEFAKELDHLVASTSKSKPN 144
            .:  |.|:       :||.||:.||::||......|:...::.|.||.|...:..|:
Human   130 PAVLGKYR-------AGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPS 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hesr	NP_525094.1	HLH	21..77	CDD:238036	19/51 (37%)
		Hairy_orange	101..>116	CDD:295407	6/14 (43%)
HES4	NP_001135939.1	HLH	62..119	CDD:238036	20/53 (38%)
		Hairy_orange	136..174	CDD:284859	14/44 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840