Protein Alignment Hesr and E(spl)m3-HLH

DIOPT Version :10

• Sequence 1: NP_525094.1
• Gene: Hesr / 32800
• FlyBaseID: FBgn0030899
• Length: 149
• Species: Drosophila melanogaster
• Sequence 2: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Alignment Length: 224
• Identity: 54/224 - (24%)
• Similarity: 87/224 - (38%)
• Gaps: 95/224 - (42%)

  Fly    16 SRSHQYREVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAVHHLSKKN- 79
            |:::|||:|.||::|||||:|||:|||.:|||:.|....:||.:.:::..|:|||.|.|:.|..
  Fly     6 SKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQ 70

  Fly    80 ----------CPVATPTTAPTSGVYQSPIDCYWSGFRECVLEVSQFL------------------ 116
                      ..|.:|.|:.::    :.::.:.||:.....:::|.|
  Fly    71 RGGLSLQGVVAGVGSPPTSTST----AHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLS 131

  Fly   117 ------------------QH-----------------NGYQPS--------FEFAKELDHLVAST 138
                              ||                 .||.|:        ..|....|.|:..|
  Fly   132 TRLIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVT 196

  Fly   139 S------------------KSKPNLWRPW 149
            |                  .|:| :||||
  Fly   197 SVDGNALSETASVSSQESGASEP-VWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hesr	NP_525094.1	bHLH_SF	16..77	CDD:469605	30/60 (50%)
		Hairy_orange	101..>116	CDD:470640	3/14 (21%)
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	31/64 (48%)
		ORANGE	96..136	CDD:128787	4/39 (10%)