Protein Alignment Hesr and HES5

DIOPT Version :10

• Sequence 1: NP_525094.1
• Gene: Hesr / 32800
• FlyBaseID: FBgn0030899
• Length: 149
• Species: Drosophila melanogaster
• Sequence 2: XP_005244808.1
• Gene: HES5 / 388585
• HGNCID: 19764
• Length: 198
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 39/183 - (21%)
• Similarity: 65/183 - (35%)
• Gaps: 64/183 - (34%)

  Fly    26 KPMMERKRRSRINRCLDFIKDLLQE--VSHLDGETMAKMDMGDVLELAVHHLSKKNCPVATPTTA 88
            ||::|:.||.|||..::.:|.||::  ..|   :..:|::..|:||:||.:|.......|....|
Human    21 KPVVEKMRRDRINSSIEQLKLLLEQEFARH---QPNSKLEKADILEMAVSYLKHSKGERARAPRA 82

  Fly    89 PTSGVYQSPI---------------------------DCYWSGFRECVLEVSQFL---------- 116
            |:|  :::|.                           ..|..|:..|:.|..|||
Human    83 PSS--HRAPAPPRPAARSPPPRLPAAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQM 145

  Fly   117 --------------------QHNGYQPSFEFAKELDHLVASTSKSKPNLWRPW 149
                                :..|..|....:.:.....|:..:....|||||
Human   146 KLLYHFQRPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRPW 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hesr	NP_525094.1	bHLH_SF	16..77	CDD:469605	19/52 (37%)
		Hairy_orange	101..>116	CDD:470640	5/14 (36%)
HES5	XP_005244808.1	bHLH-O_HES5	18..74	CDD:381467	19/55 (35%)
		Hairy_orange	118..153	CDD:470640	7/34 (21%)