Protein Alignment Hesr and Hes2

DIOPT Version :10

• Sequence 1: NP_525094.1
• Gene: Hesr / 32800
• FlyBaseID: FBgn0030899
• Length: 149
• Species: Drosophila melanogaster
• Sequence 2: NP_062109.1
• Gene: Hes2 / 29567
• RGDID: 62082
• Length: 157
• Species: Rattus norvegicus
• Alignment Length: 153
• Identity: 42/153 - (27%)
• Similarity: 70/153 - (45%)
• Gaps: 30/153 - (19%)

  Fly    20 QYREVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAVHHLSKKNCPVAT 84
            :.|:..||::|::||:|||..|..:|.|:..:...:....:|::..|:||:.|..|.::...|.:
  Rat    12 ELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCS 76

  Fly    85 PTTAPTSGVYQSPIDCYWSGFRECVLEVSQFLQHNGYQPSFEFAKELDHL-------------VA 136
             |.||.|      :|.|..|:|.|:..:::.|...........|:.|:||             .|
  Rat    77 -TEAPGS------LDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSGGPPSLTPA 134

  Fly   137 STSKSKPN----------LWRPW 149
            |.|...|:          |||||
  Rat   135 SASAPAPSPPVPPPSSLGLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hesr	NP_525094.1	bHLH_SF	16..77	CDD:469605	18/56 (32%)
		Hairy_orange	101..>116	CDD:470640	4/14 (29%)
Hes2	NP_062109.1	bHLH_SF	10..73	CDD:469605	18/60 (30%)
		ORANGE	84..128	CDD:128787	10/43 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		7/32 (22%)
		WRPW motif	154..157		2/2 (100%)