DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hesr and hes5.4

DIOPT Version :9

Sequence 1:	NP_525094.1	Gene:	Hesr / 32800	FlyBaseID:	FBgn0030899	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	XP_002933895.2	Gene:	hes5.4 / 100271766	XenbaseID:	XB-GENE-5952810	Length:	159	Species:	Xenopus tropicalis

Alignment Length:	153	Identity:	39/153 - (25%)
Similarity:	72/153 - (47%)	Gaps:	27/153 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KSRSHQYREVFKPMMERKRRSRINRCLDFIKDLLQE--VSHLDGETMAKMDMGDVLELAVHHLSK 77
            ||:: ..|::.||::|:.||.|||..:..::.||::  ..|   :..:|::..|:||:.|::|.:
Frog    16 KSKT-SLRQIRKPVVEKMRRDRINSSIKQLRMLLEKEFQRH---QPNSKLEKADILEMTVNYLKE 76

  Fly    78 KNCPVATPTTAPTSGVYQSPIDCYWSGFRECVLEVSQFLQHNGYQ--PSFEFAKELDHLV----- 135
            ....:.....|     .:||...|..|:..|:.|..|||.|...|  .:.:..:..:..|
Frog    77 HQLQMNAVAFA-----RKSPFQDYNQGYSRCLEETLQFLSHTEMQKPANLKLVQHFNRTVPADNN 136

  Fly   136 ---ASTSKSKPN------LWRPW 149
               .:.|..:|:      :||||
Frog   137 LPQGAPSLKQPSSNTAAIIWRPW 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hesr	NP_525094.1	HLH	21..77	CDD:238036	18/57 (32%)
Hesr	NP_525094.1	Hairy_orange	101..>116	CDD:295407	5/14 (36%)
hes5.4	XP_002933895.2	bHLH-O_HES5	23..81	CDD:381467	17/60 (28%)
hes5.4	XP_002933895.2	Hairy_orange	93..129	CDD:413415	9/35 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920