DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frq2 and guca1a

DIOPT Version :9

Sequence 1:	NP_001259675.1	Gene:	Frq2 / 32799	FlyBaseID:	FBgn0083228	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_571945.1	Gene:	guca1a / 140430	ZFINID:	ZDB-GENE-011128-5	Length:	189	Species:	Danio rerio

Alignment Length:	175	Identity:	62/175 - (35%)
Similarity:	103/175 - (58%)	Gaps:	17/175 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFP----DGDPSKFASLVFRVF 72
            |:|.|..      .|:..|:|.|:.:||:|.||    :..:||||.    |...:.:...:||.|
Zfish     8 TVDDLQA------VEMHLWYKKFMTECPSGQLT----LHEFKQFFGLRGLDPKANAYIEQMFRTF 62

  Fly    73 DENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQ 137
            |.|.||.|:|.|::.|||:..||.::.||.|.|:|||||.:|.|.|.|:.||:.||..:.|.:.|
Zfish    63 DMNKDGYIDFMEYVAALSLVMRGKMEHKLRWYFKLYDVDGNGCIDRYELLNIIKAIRAINGSETQ 127

  Fly   138 TEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRIVQAL 182
               |::.::..:::|:::|.|.|..|:|:||..|:::|...::.:
Zfish   128 ---ESSAEEFTNRVFERIDINGDGELSLDEFVAGARSDEEFMEVM 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frq2	NP_001259675.1	FRQ1	9..178	CDD:227455	62/169 (37%)
guca1a	NP_571945.1	EFh	<27..76	CDD:298682	20/52 (38%)
		EFh	54..116	CDD:238008	30/61 (49%)
		EF-hand_7	55..115	CDD:290234	29/59 (49%)
		EFh	90..160	CDD:238008	29/72 (40%)
		EF-hand_7	91..157	CDD:290234	27/68 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810