DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frq1 and Kcnip3

DIOPT Version :9

Sequence 1:	NP_001033853.1	Gene:	Frq1 / 32797	FlyBaseID:	FBgn0030897	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001277934.1	Gene:	Kcnip3 / 56461	MGIID:	1929258	Length:	284	Species:	Mus musculus

Alignment Length:	187	Identity:	76/187 - (40%)
Similarity:	119/187 - (63%)	Gaps:	8/187 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SKLKQDTI-------DRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSK 63
            |:|:..|:       |:|...|.||:||::..::||..:||.||:.|..|..||.|||||||.:.
Mouse    93 SELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATT 157

  Fly    64 FASLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAI 128
            :|..:|..||.:.:|:|.||:|:..||:..:|.:.|||:|||.|||::.||.||:|||..|:.:|
Mouse   158 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 222

  Fly   129 YQMVGQQPQS-EDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSL 184
            |.|:|:.... ..|:.|.:.|::.|.:||:|.||.:|::||.|..:.|..|:.::.|
Mouse   223 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frq1	NP_001033853.1	FRQ1	9..178	CDD:227455	72/176 (41%)
Kcnip3	NP_001277934.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..57
		FRQ1	109..273	CDD:227455	70/163 (43%)
		EFh	158..220	CDD:238008	29/61 (48%)
		EFh	194..265	CDD:238008	32/70 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810