DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frq1 and Kcnip4

DIOPT Version :9

Sequence 1:	NP_001033853.1	Gene:	Frq1 / 32797	FlyBaseID:	FBgn0030897	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_852030.1	Gene:	Kcnip4 / 259243	RGDID:	708539	Length:	250	Species:	Rattus norvegicus

Alignment Length:	178	Identity:	74/178 - (41%)
Similarity:	124/178 - (69%)	Gaps:	3/178 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFASLVFRVFD 73
            :.:.::.|...:.||:||::..::||..:||:|::.|:.|.:||.|||||||.:.:|..:|..||
  Rat    69 RPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFD 133

  Fly    74 ENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQ--QP 136
            .:::|::.||:||:.||:..:|.:.|||.|||.|||::.|||||:|||.:|:.|||.|:|:  .|
  Rat   134 TDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYP 198

  Fly   137 QSEDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSL 184
            ..: |:.|::.|:..|.:||||.||.:|::||.|..:.|..|::::.|
  Rat   199 VLK-EDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQL 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frq1	NP_001033853.1	FRQ1	9..178	CDD:227455	72/170 (42%)
Kcnip4	NP_852030.1	KIS. /evidence=ECO:0000250	2..44
		FRQ1	80..239	CDD:227455	71/159 (45%)
		Interaction with KCND2. /evidence=ECO:0000250	237..250		2/9 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810