DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frq1 and Rcvrn

DIOPT Version :9

Sequence 1:	NP_001033853.1	Gene:	Frq1 / 32797	FlyBaseID:	FBgn0030897	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_033064.1	Gene:	Rcvrn / 19674	MGIID:	97883	Length:	202	Species:	Mus musculus

Alignment Length:	188	Identity:	83/188 - (44%)
Similarity:	126/188 - (67%)	Gaps:	8/188 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MG-KKSSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKF 64
            || .||..|.::.::.|..:|.|||:|:..|::.|||:||:|.:|.|.|..||.:|||..||..:
Mouse     1 MGNSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKFFPDSDPKAY 65

  Fly    65 ASLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIY 129
            |..|||.||.|:||:::|:|::.||.:|:.|...:||:|||.|||||.:|.|::.|:..||.||:
Mouse    66 AQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIVMAIF 130

  Fly   130 QMVGQQPQS-----EDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQAL 182
            :|:  :|:.     :|||||:||.:||:....|..|.|||.|||.||:.|:..|::.:
Mouse   131 KMI--KPEDVKLLPDDENTPEKRAEKIWAFFGKKEDDKLTEEEFIEGTLANKEILRLI 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frq1	NP_001033853.1	FRQ1	9..178	CDD:227455	77/173 (45%)
Rcvrn	NP_033064.1	FRQ1	14..182	CDD:227455	77/169 (46%)
		EFh	<37..90	CDD:298682	25/52 (48%)
		EFh	65..127	CDD:238008	29/61 (48%)
		EFh	101..175	CDD:238008	36/75 (48%)
		Interaction with GRK1. /evidence=ECO:0000250\|UniProtKB:P21457	189..192
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810