DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frq1 and ncs-1

DIOPT Version :9

Sequence 1:	NP_001033853.1	Gene:	Frq1 / 32797	FlyBaseID:	FBgn0030897	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_508186.1	Gene:	ncs-1 / 180448	WormBaseID:	WBGene00003563	Length:	191	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	134/188 - (71%)
Similarity:	157/188 - (83%)	Gaps:	1/188 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKKSSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFA 65
            |||.:||||...|..|...||||||||:||:|||::|||||:|||.||.|||||||||||||.||
Worm     1 MGKGNSKLKSSQIRDLAEQTYFTEKEIKQWYKGFVRDCPNGMLTEAGFQKIYKQFFPQGDPSDFA 65

  Fly    66 SLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIYQ 130
            |.||:|||||.||:|||.|||||||:||:|||||||.|||:|||:|.||:|||.||.:|||:||:
Worm    66 SFVFKVFDENKDGAIEFHEFIRALSITSRGNLDEKLHWAFKLYDLDQDGFITRNEMLSIVDSIYK 130

  Fly   131 MVGQQPQ-SEDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSLGGG 187
            |||...| .|:||||:||||:||..||||:|.:||||||:||:||||.||.||||..|
Worm   131 MVGSSVQLPEEENTPEKRVDRIFRMMDKNNDAQLTLEEFKEGAKADPSIVHALSLYEG 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frq1	NP_001033853.1	FRQ1	9..178	CDD:227455	121/169 (72%)
ncs-1	NP_508186.1	FRQ1	11..179	CDD:227455	120/167 (72%)
		EFh	67..125	CDD:238008	42/57 (74%)
		EFh	100..174	CDD:238008	49/73 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159630
Domainoid	1	1.000	109	1.000	Domainoid score	I3990
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5719
Inparanoid	1	1.050	282	1.000	Inparanoid score	I1743
Isobase	1	0.950	-	0	Normalized mean entropy	S161
OMA	1	1.010	-	-		QHG28990
OrthoDB	1	1.010	-	-		D1369072at2759
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	1	1.000	-	-		otm14324
orthoMCL	1	0.900	-	-		OOG6_100764
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R801
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750