Protein Alignment ari-1 and RNF144A

DIOPT Version :10

• Sequence 1: NP_523399.1
• Gene: ari-1 / 32796
• FlyBaseID: FBgn0017418
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001336110.1
• Gene: RNF144A / 9781
• HGNCID: 20457
• Length: 318
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 63/212 - (29%)
• Similarity: 93/212 - (43%)
• Gaps: 33/212 - (15%)

  Fly   133 CEICFSQLPPDSMAGL-ECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGC----DILVDDVTV 192
            |::|..:.|.:.|..: :|...||..|..:|:.. ::.|||...|||....|    .:..:::
Human    20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVEL-LIKEGLETAISCPDAACPKQGHLQENEI-- 81

  Fly   193 ANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVK---VPYAEPRRVHCK-CGHVFCFA 253
             ..:..|.:..:|::|.....|..:....|||:..|....:   |....|:.|.|| |...||..
Human    82 -ECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCST 145

  Fly   254 CGENWHDPVKC------RWL----KKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMV 308
            |..:||....|      .:|    ....|..:||        |..|.||:|.|.||:|.||..|:
Human   146 CKASWHPGQGCPETMPITFLPGETSAAFKMEEDD--------APIKRCPKCKVYIERDEGCAQMM 202

  Fly   309 CKNQNCKNEFCWVCLGS 325
            ||  |||:.|||.||.|
Human   203 CK--NCKHAFCWYCLES 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_523399.1	RING-HC_RBR_HHARI	131..189	CDD:438288	16/60 (27%)
		BRcat_RBR_HHARI-like	198..279	CDD:439004	24/94 (26%)
		Rcat_RBR_HHARI-like	283..340	CDD:439017	23/43 (53%)
		Ariadne	341..>459	CDD:466073
RNF144A	NP_001336110.1	mRING-HC-C4C4_RBR_RNF144A	18..72	CDD:438433	16/52 (31%)
		BRcat_RBR_RNF144A	99..163	CDD:439027	17/63 (27%)
		Rcat_RBR_RNF144	178..247	CDD:439013	25/50 (50%)