DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-1 and ARI5

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001184920.1	Gene:	ARI5 / 837099	AraportID:	AT1G05890	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	166/542 - (30%)
Similarity:	246/542 - (45%)	Gaps:	101/542 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSDNDNDFCDNVD----SGNVSSGDDGDD-DFGM-EVDLPSSAD-------------------- 39
            ||||:|....|:||    ||.....:|.|: |||. |.|...:|.
plant     1 MDSDDDMHDMDSVDYDYYSGGTYDDNDSDETDFGFGEADTDDAAIIASYRSKVASILVSCFGLLL 65

  Fly    40 ---RQMD-------------------QDDYQYKVLTTDEIVQHQREIIDEANLLLKLPTPTTRIL 82
               |.::                   ..:..|.||..::|.:||.:.:...:.:|.:.......|
plant    66 QRWRMLEAVFCLFVCFFFFGLRLLLYSCNSNYVVLKEEDIRRHQNDDVGRVSAVLSITDVEASTL 130

  Fly    83 LNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPFNATEAIKQKTSRSQCEECEICFSQLPPDSMAG 147
            |.|:.|...|:.:::|.|..........:..|...|...::.|       |.|||.....:.:..
plant   131 LLHYHWSVSKVNDEWFADEERVRRTVGILEGPVVTTPDGREFT-------CGICFDSYTLEEIVS 188

  Fly   148 LECGHRFCMPCWHEYLSTKIVAEGLGQTI------SC-AAHGCDILVDDVTVANLVTDARVRVKY 205
            :.|||.||..||..|:||.| .:|.|..:      || ||.|.|::       :.:.....:.||
plant   189 VSCGHPFCATCWTGYISTTI-NDGPGCLMLKCPDPSCPAAIGRDMI-------DKLASKEDKEKY 245

  Fly   206 QQLITNSFVECNQLLRWCPSVDCTYAVKVPYA---EPRRVHCKCGHVFCFACGENWHDPVKCRWL 267
            .:....|:||.|:.::|||:..|.:|  :.:|   |...|.|.|.|.||:.|.|..|.||.|..:
plant   246 YRYFLRSYVEVNREMKWCPAPGCEHA--IDFAGGTESYDVSCLCSHSFCWNCTEEAHRPVDCDTV 308

  Fly   268 KKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVCLGSWEPHG-- 330
            .|||.|...:||..|||.||:|.||:|...|||:.||.||.| ...||.||||:||.:|..||
plant   309 GKWILKNSAESENMNWILANSKPCPKCKRPIEKNHGCMHMTC-TPPCKFEFCWLCLNAWTEHGER 372

  Fly   331 -SSWYNCNRYDE-------DEAKTARDAQEKLRSSLARYLHYYNRY-MNHMQSMKFENKLYASVK 386
             ..:|.||||:.       |||:..|   |..::||.||.|||.|: .|.:...|....|
plant   373 TGGFYACNRYEAAKQEGLYDEAERRR---EMAKNSLERYTHYYERWASNQVSRQKAMGDL----- 429

  Fly   387 QKMEEMQQHNMSWI------EVQFLKKAVDILCQCRQTLMYTYVFAYYLKKNNQSMIFEDNQKDL 445
            |||:..:...:|.|      :::|:.:|...:.:||:.|.:||.:.|||:.:.:...||..|.:.
plant   430 QKMQSEKLGKLSDIQCTPESQLKFIAEAWLQIIECRRVLKWTYAYGYYLQDHAKKPFFEYLQGEA 494

  Fly   446 ESATEMLSEYLERDITSENLAD 467
            ||..|.|.:.:|:||....||:
plant   495 ESGLERLHKCVEKDIEVFELAE 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	24/62 (39%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	22/39 (56%)
ARI5	NP_001184920.1	IBR	243..305	CDD:214763	24/63 (38%)
ARI5	NP_001184920.1	IBR	<327..366	CDD:279784	22/39 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3141
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1045
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.690