DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-1 and ARI12

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001184919.1	Gene:	ARI12 / 837098	AraportID:	AT1G05880	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	118/531 - (22%)
Similarity:	209/531 - (39%)	Gaps:	113/531 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DGDDDFGMEVDLPSS--------ADRQMDQDDYQ--YKVLTTDEIVQHQREI-IDEANLLLKLPT 76
            |.:...|.|||..:.        .|.|..:...|  |..:.|:|.::...|| :...:....|..
plant     2 DNNSVIGSEVDAEADESYVNAALEDGQTGKKSVQRNYATVLTEEDIRALMEIDVQSVSDFTSLSK 66

  Fly    77 PTTRILLNHFKWDKEKLLEKY-------------------FDDNTDEFFKCAHVINPFNATEAIK 122
            ....:||:|.:|:.:.:.:::                   .|||  |:|
plant    67 AEATLLLSHLRWNVDCICKQWSAGAQSVRDSVGLLELDPPSDDN--EYF---------------- 113

  Fly   123 QKTSRSQCEECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAE--------------GLG 173
                      |..|....|..::|.:.||||.|..||..::: ||::|              .:|
plant   114 ----------CGACGESHPHKNLASVSCGHRICTRCWTSHIN-KIISEKPAAEWNLWLKCPVRVG 167

  Fly   174 QTISC-AAHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKV-PY 236
            ...|| |:.|.|      |:....: .|.:..|.|.:..|:|:..:.::|.|......|:.: |.
plant   168 LHASCPASVGLD------TIERFAS-KREKFNYNQYLLRSYVDNRETMKWHPIQGSRCAIDLSPG 225

  Fly   237 AEPRRVHCKCGHVFCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKD 301
            :....|.|.....||:.|.|:.|.||.|:...||:.:             |...||:|.:.|.::
plant   226 SGNASVSCHRLVRFCWNCREDAHSPVDCKTAAKWLLE-------------NAVPCPKCKLRIPRN 277

  Fly   302 GGCNHMVCKNQNCKNEFCWVCLGSW----EPHGSSWYNCNRYDEDEAKTARDAQEKL-RSSLARY 361
            .. |.:..|...|...|||.|...|    |..|...:.|. :|    ....|.:.|: .|...||
plant   278 QD-NSLKMKCLPCNYVFCWFCHVDWIEDMEGTGGDLHFCT-FD----AVLSDQRGKMSESDSNRY 336

  Fly   362 LHYYNRY-MNHMQSMKFENKL--YASVKQKMEEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTY 423
            ...|..: .|.:...|.:..|  ..::.|::...|..|:|  :::|:.:|...:.:||:.|.:||
plant   337 EDCYENWDSNELLMQKEQANLPKLDTIIQELSNTQLENVS--QLKFILEAGLQIIECRRVLEWTY 399

  Fly   424 VFAYYLKKN--NQSMIFEDNQKDLESATEMLSEYLERDITSENLADIKQKVQDKYRYCEKRCSVL 486
            |:.|||:::  .:..:.:|.|:.|:...|.|...||.::......:...|..:.:|......:.|
plant   400 VYGYYLREDEVGKQNLLKDTQERLKKFVENLKHCLETNLQPFRYEEEPSKDFNAFRIKLTELTSL 464

  Fly   487 LKHVHEGYDKE 497
            .::.:|...|:
plant   465 TRNHYENVVKD 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	17/60 (28%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	12/39 (31%)
ARI12	NP_001184919.1	Zn_Tnp_IS91	<111..>139	CDD:291017	11/53 (21%)
		IBR	193..253	CDD:214763	17/59 (29%)
		IBR	<266..301	CDD:303000	11/35 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3648
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1045
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.790