DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-1 and ARI14

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_201178.1	Gene:	ARI14 / 836493	AraportID:	AT5G63730	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	120/528 - (22%)
Similarity:	198/528 - (37%)	Gaps:	136/528 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 YKVLTTDEIVQHQREIIDEANLLLKLPTPTTRILLNHFKWD-----------KEKLLEKYFDDNT 102
            |.|||.:||....::.|:|.:.:..:......:||.:.:||           |||||       .
plant     9 YSVLTRNEITVKMKKQINEISDIFFISNSDATVLLMYLRWDSLRVSERLGENKEKLL-------M 66

  Fly   103 DEFFKCAHVINPFNATEAIKQKTSRSQCE-ECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTK 166
            |...|.. :|:|        ...|.|:.. |.::.......|.::...|.|:|....|.|||...
plant    67 DSGLKSV-MIDP--------SPDSSSEISLETDVYEFDGDNDLISMPFCSHKFDSKYWREYLEKN 122

  Fly   167 I-VAEGLGQTISCAAHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLL--RWCPSVDC 228
            . ..|.:..||||....|...|...|:..|.  .|.:..|::.|..|::|.|::|  :.||:.:|
plant   123 FYYVEKIQTTISCPDQDCRSAVGPDTIEKLT--VRDQEMYERYIWRSYIEGNKVLMIKQCPARNC 185

  Fly   229 TYAVKV--------PYAEPRRVHCKCGHVFCFACGENWHDPVKCR----WLKKWIKKCDDDSETS 281
            .|.::.        .|:  ..|.|.|||:||:.|....|.||.|.    ||.....|..|:|.:.
plant   186 DYVIEFHQENDDDDEYS--LNVVCICGHIFCWRCRLESHRPVSCNKASDWLCSATMKISDESFSL 248

  Fly   282 NWIAANTKECPRCSVTIEKDGGC-NHMVCKNQNCKNEFCWVCLGSWEPHGSSWYN---CNRYD-- 340
            ......|..||.|..::|.|... ..:.|.   |:..||..||.|.|.|.....:   |.:.:
plant   249 YPTKTKTVTCPHCLCSLESDTKMPQFLTCV---CRLRFCSRCLRSEEAHKIEAVDSGFCIKTEVG 310

  Fly   341 ---EDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYASVKQKMEEMQQHNMSWIEV 402
               ||.....:...|:.:|.|.                .||.   .::|:..:.:::.     ::
plant   311 ILCEDRWNVCQKLLEQAKSDLE----------------AFEE---TNIKKPSDLLREQ-----DI 351

  Fly   403 QFLKKAVDILCQCRQTLMYTYVFAY-------------YLKKN------NQSMIFEDNQKD---- 444
            ..:::.:.::.|||:.|.:..|:.|             ||:.|      :.|...:: |||
plant   352 MIIREGLMLIVQCRRVLKWCCVYDYFHTEYENSKEYLRYLQGNAIATLQSYSNTLQE-QKDIVLA 415

  Fly   445 -------------LESATEMLSEYLE--RDITSENLADIKQKVQD----KYRYCEKRCSVLLKHV 490
                         :.:||..:..|..  .....:.|.|:|.|..:    .:.||: ||:
plant   416 AATYEECTFFRHTIPTATSNIGNYFYDFMKTLQDGLVDVKVKSYNGGTGPFWYCD-RCT------ 473

  Fly   491 HEGYDKEW 498
               |...|
plant   474 ---YANTW 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	22/69 (32%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	12/40 (30%)
ARI14	NP_201178.1	IBR	158..227	CDD:214763	22/70 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3648
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.780