DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-1 and ARI1

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_567966.1	Gene:	ARI1 / 829587	AraportID:	AT4G34370	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	157/481 - (32%)
Similarity:	241/481 - (50%)	Gaps:	65/481 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NDNDFCDNVDSGNVSSGDDGDDDFGMEVDL-PSSADRQMDQDDYQYKVLTTDEIVQHQREIIDEA 68
            :|.|..|.:|:              .|.:| |.|:.|...|      |:|.:.::..|||.:...
plant    16 SDQDSLDGIDN--------------EESELQPLSSKRSNTQ------VITQESLLAAQREDLLRV 60

  Fly    69 NLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPFN---ATEAIKQKTSRSQC 130
            ..||.:.....|.||.|::||.|||...:.:...|..|..|.| ..|:   ...:..|.:..|
plant    61 MELLSIKEHHARTLLIHYQWDVEKLFAVFVEKGKDSLFSGAGV-TVFDYQYGNSSFPQSSQMS-- 122

  Fly   131 EECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANL 195
              |::|...||.|.|..::|||.||..||.|:.:.:| .||..:.|.|.||.|:.:.|:..|.:|
plant   123 --CDVCMEDLPGDHMTRMDCGHCFCNNCWTEHFTVQI-NEGQSKRIRCMAHQCNAICDEDIVRSL 184

  Fly   196 VTDAR--VRVKYQQLITNSFVECNQLLRWCPSV-DCTYAVKVPYAEPRRVHCKCGHVFCFACGEN 257
            |:..|  :..|:.:.:..|::|.|::::||||. .|..|::....:...|.|.||..|||:|...
plant   185 VSKKRPDLAAKFDRYLLESYIEDNRMVKWCPSTPHCGNAIRAEDDKLCEVECSCGLQFCFSCLCQ 249

  Fly   258 WHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVC 322
            .|.|..|...:.|.|||.|:|||.|||..:||.||:|...:||:||||.:.|....|   |||:|
plant   250 AHSPCSCLMWELWRKKCRDESETINWITVHTKLCPKCYKPVEKNGGCNLVRCICGQC---FCWLC 311

  Fly   323 ---LGSWEPHGS-SWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYA 383
               .||...:.| :.::|.||.:|:.|    ..|:.:..|.||.||::||..|..|.|.|:||..
plant   312 GGATGSDHTYRSIAGHSCGRYQDDKEK----QMERAKRDLNRYTHYHHRYKAHTDSSKLEDKLRD 372

  Fly   384 SVKQKMEEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTYVFAYY-----------------LKK 431
            ::.:|:.:.::..:...:..::...:|.|.:.|:.|.|:|.||||                 :||
plant   373 TIHEKVSKSEKRELKLKDFSWVTNGLDRLFRSRRVLSYSYAFAYYMFGEEMFKDEMTPEEREIKK 437

  Fly   432 NNQSMIFEDNQKDLESATEMLSEYLE 457
            |    :|||.|:.|||..|.||::||
plant   438 N----LFEDQQQQLESNVEKLSQFLE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	20/60 (33%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	18/42 (43%)
ARI1	NP_567966.1	IBR	194..256	CDD:214763	20/61 (33%)
ARI1	NP_567966.1	IBR	<284..313	CDD:279784	14/31 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	81	1.000	Domainoid score	I2944
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H111871
Inparanoid	1	1.050	260	1.000	Inparanoid score	I974
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1176
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X447
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830