DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ari-1 and SHARPIN

DIOPT Version :9

Sequence 1:NP_001245736.1 Gene:ari-1 / 32796 FlyBaseID:FBgn0017418 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_112236.3 Gene:SHARPIN / 81858 HGNCID:25321 Length:387 Species:Homo sapiens


Alignment Length:40 Identity:11/40 - (27%)
Similarity:15/40 - (37%) Gaps:14/40 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   291 CPRCSVTIEKD-GGCNHMVCKNQN-CKNEFCWVCLGSWEP 328
            ||.|:.....| .||.  :|..|. |          :|:|
Human   354 CPSCTFINAPDRPGCE--MCSTQRPC----------TWDP 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ari-1NP_001245736.1 IBR 204..264 CDD:214763
IBR <286..326 CDD:279784 9/36 (25%)
SHARPINNP_112236.3 Self-association. /evidence=ECO:0000250|UniProtKB:Q9EQL9 1..180
Sharpin_PH 29..126 CDD:293369
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 122..169
Interaction with SHANK1. /evidence=ECO:0000250|UniProtKB:Q9EQL9 175..310
UBQ 240..300 CDD:294102
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..349
ZnF_RBZ 351..373 CDD:197784 7/20 (35%)
RanBP2-type Zn finger 352..371 CDD:275376 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1815
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.