DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-1 and ARI9

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_180736.1	Gene:	ARI9 / 817734	AraportID:	AT2G31770	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	162/488 - (33%)
Similarity:	248/488 - (50%)	Gaps:	53/488 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NDNDFCDNVDSG--NVS-SGDDGDDDFGMEVD--LPSSADRQMDQDDYQYKVLTTDEIVQHQREI 64
            :|:|..|| .||  |.| .|.:..||:...||  :||         :..|.:|..::|::.||:.
plant     4 SDDDMIDN-KSGEENYSYGGGNESDDYNDVVDTIIPS---------EKSYVILKEEDILKLQRDD 58

  Fly    65 IDEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVIN----PFNATEAIKQKT 125
            |:..:.:|.|......:||.|:.|...|:.:::|.|. :...|...::.    .||..|  |.|.
plant    59 IERVSSILSLSQVEVIVLLLHYNWCVSKVEDEWFTDE-ERIRKAVGLLKEPVVDFNGGE--KDKK 120

  Fly   126 SRSQCEECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLG-QTISC------AAHGC 183
            .|....:|.|||.....:.:|.:.|||.:|..||..|::||| .:|.| ..:.|      ||.|.
plant   121 CRKVNIQCGICFESYTREEIARVSCGHPYCKTCWAGYITTKI-EDGPGCLRVKCPEPSCSAAVGK 184

  Fly   184 DILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAEPRR--VHCKC 246
            |::.|       ||:.:|..||.:.|..|:||..:.::||||..|.|||:...:|...  |.|.|
plant   185 DMIED-------VTETKVNEKYSRYILRSYVEDGKKIKWCPSPGCGYAVEFGGSESSSYDVSCLC 242

  Fly   247 GHVFCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKN 311
            .:.||:.|.|:.|.||.|..:.|||.|..|:||..||:.||:|.||.|...|||:.|||||.| :
plant   243 SYRFCWNCSEDAHSPVDCDTVSKWIFKNQDESENKNWMLANSKPCPECKRPIEKNDGCNHMTC-S 306

  Fly   312 QNCKNEFCWVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQS-M 375
            ..|.:||||:||.::..|..:   |||:..::|::.|   ..|:|.:.||.|||.|:..:..| :
plant   307 APCGHEFCWICLKAYRRHSGA---CNRFVVEQAESKR---ALLQSEIKRYTHYYVRWAENQSSRL 365

  Fly   376 KFENKLYASVKQKMEEMQQHN-MSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLKKNNQSMIFE 439
            |....|......:::|:..:. .|..::||...|...:.:||:.|.:||.:.|||:...:...||
plant   366 KAMRDLEKLQSVQLKELSDNQCTSETQLQFTVDAWLQIIECRRVLKWTYAYGYYLQDLPKRKFFE 430

  Fly   440 DNQKDLESATEMLSEYLERD-----ITSENLAD 467
            ..|.:.||..|.|....|.:     |.||:.:|
plant   431 YLQGEAESGLERLHHCAENELKQFFIKSEDPSD 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	25/61 (41%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	22/39 (56%)
ARI9	NP_180736.1	RING-HC_RBR_TRIAD1_like	128..178	CDD:319537	18/50 (36%)
		IBR	197..260	CDD:214763	25/62 (40%)
		IBR	<282..326	CDD:396187	23/44 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3141
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1045
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.690