DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-1 and ARI2

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_179206.2	Gene:	ARI2 / 816106	AraportID:	AT2G16090	Length:	593	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	155/493 - (31%)
Similarity:	242/493 - (49%)	Gaps:	54/493 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SDNDNDFCDNVDSGNVSSGDDGDDDFGMEVDLPSSADRQMDQDDYQYKVLTTDEIVQHQREIIDE 67
            |..:.|:..:.|..:: :|.|.|:...:.|...|:.          .||:|.:.::..|||.:..
plant     6 SGEEEDYYYSSDQESL-NGIDNDESVSIPVSSRSNT----------VKVITKESLLAAQREDLRR 59

  Fly    68 ANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPFNATEAIKQKTSRSQCEE 132
            ...||.:.....|.||.|::||.|||.....:...|..|..|.|....|.: .....:..|....
plant    60 VMELLSVKEHHARTLLIHYRWDVEKLFAVLVEKGKDSLFSGAGVTLLENQS-CDSSVSGSSSMMS 123

  Fly   133 CEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANLVT 197
            |:||...:|...:..::|||.||..||..:.:.|| .||..:.|.|.||.|:.:.|:..|..||:
plant   124 CDICVEDVPGYQLTRMDCGHSFCNNCWTGHFTVKI-NEGQSKRIICMAHKCNAICDEDVVRALVS 187

  Fly   198 DAR--VRVKYQQLITNSFVECNQLLRWCPSV-DCTYAVKVPYAEPRRVHCKCGHVFCFACGENWH 259
            .::  :..|:.:.:..|::|.|::::||||. .|..|::|...|...|.|.||..|||:|....|
plant   188 KSQPDLAEKFDRFLLESYIEDNKMVKWCPSTPHCGNAIRVEDDELCEVECSCGLQFCFSCSSQAH 252

  Fly   260 DPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVCLG 324
            .|..|...:.|.|||.|:|||.|||..:||.||:|...:||:||||.:.|.   |:..|||:| |
plant   253 SPCSCVMWELWRKKCFDESETVNWITVHTKPCPKCHKPVEKNGGCNLVTCL---CRQSFCWLC-G 313

  Fly   325 SWEPHGSSW-----YNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYAS 384
            .......:|     ::|.|:.||:.|    ..|:.:..|.||:||:|||..|:.|.|.|.||..:
plant   314 EATGRDHTWARISGHSCGRFQEDKEK----QMERAKRDLKRYMHYHNRYKAHIDSSKLEAKLSNN 374

  Fly   385 VKQKM-----EEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYL-------------KK 431
            :.:|:     .|:|..:.||     ....:..|.:.|:.|.|:|.||:|:             ::
plant   375 ISKKVSISEKRELQLKDFSW-----ATNGLHRLFRSRRVLSYSYPFAFYMFGDELFKDEMSSEER 434

  Fly   432 NNQSMIFEDNQKDLESATEMLSEYLERDITSENLADIK 469
            ..:..:|||.|:.||:..|.||::||...  :..||.|
plant   435 EIKQNLFEDQQQQLEANVEKLSKFLEEPF--DQFADDK 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	22/60 (37%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	18/39 (46%)
ARI2	NP_179206.2	RING_Ubox	126..174	CDD:418438	18/48 (38%)
		IBR	195..257	CDD:214763	22/61 (36%)
		IBR	<283..314	CDD:396187	15/34 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	81	1.000	Domainoid score	I2944
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H111871
Inparanoid	1	1.050	260	1.000	Inparanoid score	I974
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1176
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X447
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830