DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-1 and Cul7

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	XP_006244637.1	Gene:	Cul7 / 680835	RGDID:	1587048	Length:	1698	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	46/256 - (17%)
Similarity:	90/256 - (35%)	Gaps:	91/256 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 GENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFC 319
            |.|.|...:.|||   |.:..||.::|                             ..:||.|..
  Rat    31 GHNGHPEYQIRWL---ILRRGDDGDSS-----------------------------QVDCKAEHI 63

  Fly   320 WVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYAS 384
            .:    |......:.||::...::.:..|.:||...:.                         |.
  Rat    64 LL----WMTDDEIYANCHKMLGEDGQVIRPSQESAEAG-------------------------AL 99

  Fly   385 VKQKMEEMQQHNMSWIEVQFLKKAVDILCQC-----RQTLMYT-YVFAYYLKKNNQSMIFEDNQK 443
            .|..:.||:....|.|:     :|:..|.:|     ...|::| :|.:.|......:.:|:| ::
  Rat   100 DKSVLGEMETDVKSLIQ-----RALRQLEECVGAVPPAPLLHTVHVLSAYASIEPLTGVFKD-RR 158

  Fly   444 DLESATEMLS--EY--------LERDITSEN--------LADIKQKVQDKYRYCEKRCSVL 486
            .|:....|||  :|        :.:.::|.:        |:..:|:..:|:...:.||::|
  Rat   159 VLDLVMHMLSSPDYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	3/8 (38%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	3/39 (8%)
Cul7	XP_006244637.1	Cul7	351..421	CDD:402903
		APC10-like	821..951	CDD:382862
		COG5647	<1391..1639	CDD:227934
		Cullin	<1391..1509	CDD:395716
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010