DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-1 and rbck1

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001002168.1	Gene:	rbck1 / 431715	ZFINID:	ZDB-GENE-040704-3	Length:	515	Species:	Danio rerio

Alignment Length:	335	Identity:	72/335 - (21%)
Similarity:	118/335 - (35%)	Gaps:	122/335 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DDYQYKVLTTDEI--VQHQREIIDEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFK 107
            |:.:.:.|..:|:  :|:::.::.|                     ::...||:  ..|.:|..:
Zfish   231 DESETRRLQQEELASLQYEQSLLQE---------------------EERNFLER--QRNYEELLQ 272

  Fly   108 CAHVINPFNATEAIKQKTSRSQCEECEICFSQLPPDSMAGL-ECGHRFCMPCWHEYLSTKIVAEG 171
                      |:|.....:..|. ||.|||..:.|...|.| ||.|.||..|....:...:.||
Zfish   273 ----------TDAHSLVGNTDQL-ECAICFGTIMPGEGAVLRECLHSFCRDCLKGTVVNCLDAE- 325

  Fly   172 LGQTISCA----AHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAV 232
                :.|.    |:.|:..:.|..:.:|:|    :.:||:     |:|                :
Zfish   326 ----VCCPYGDNAYACNCKLQDREIKSLLT----QDEYQK-----FLE----------------L 361

  Fly   233 KVPYAEPR---RVHCK---------------------CGHVFCFACGENWHDPVKCRWLKKWIKK 273
            ::..||.|   ..|||                     |....|..| :..|..:.|       |:
Zfish   362 RLNIAESRSENSYHCKTPDCAGWCIFEDDVNEFKCDICNETNCLLC-KAIHKGMNC-------KE 418

  Fly   274 CDDDSET---SNWIAANTKE-------------CPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVC 322
            ..||...   ::..|..|.|             ||:|.|.::|..||:.:.|  ..||.|.|||.
Zfish   419 YQDDLRVRAQNDEAARQTTEMLDQLLKNGEAMNCPKCQVIVQKKDGCDWICC--LMCKTEICWVT 481

  Fly   323 -LGSWEPHGS 331
             ...|.|.|:
Zfish   482 KQARWGPLGA 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	14/83 (17%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	16/53 (30%)
rbck1	NP_001002168.1	UBQ	62..136	CDD:320785
		RanBP2-type Zn finger	195..214	CDD:275376
		RING_Ubox	283..337	CDD:327409	19/59 (32%)
		IBR	356..409	CDD:307574	12/74 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900