DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-1 and Rnf19b

DIOPT Version :9

Sequence 1:	NP_001245736.1	Gene:	ari-1 / 32796	FlyBaseID:	FBgn0017418	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	XP_008762369.2	Gene:	Rnf19b / 313806	RGDID:	1305470	Length:	730	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	64/217 - (29%)
Similarity:	94/217 - (43%)	Gaps:	41/217 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 ECEICFSQLPPDSMAG-LECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANL 195
            ||.:|..:|||:.... |.|.||.|..|...||..:|....:  .|||..  |...::...:..|
  Rat   112 ECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSERLNPHDIRLL 172

  Fly   196 VTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPY--AEPRRVHCK---CGHVFCFACG 255
            :.|..:..||::.:...::..:...||||:.||.||| :.|  |...::.|:   |...||:.|.
  Rat   173 LADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTCEREGCQTEFCYHCK 236

  Fly   256 ENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKE-----------------CPRCSVTIEK--D 301
            :.||....|...::         :.:..:...||.                 |||||..|.|  |
  Rat   237 QIWHPNQTCDMARQ---------QRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMND 292

  Fly   302 GGCNHMVCKNQNCKNEFCWVCL 323
            |.||||.|....|  ||||:|:
  Rat   293 GSCNHMTCAVCGC--EFCWLCM 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-1	NP_001245736.1	IBR	204..264	CDD:214763	20/64 (31%)
ari-1	NP_001245736.1	IBR	<286..326	CDD:279784	22/57 (39%)
Rnf19b	XP_008762369.2	RING_Ubox	113..166	CDD:418438	18/56 (32%)
		RING-HC finger (C3HC4-type)	113..160	CDD:319361	17/50 (34%)
		IBR	181..245	CDD:214763	20/64 (31%)
		IBR	<276..314	CDD:396187	20/39 (51%)
		AzlC	<340..429	CDD:412452
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810