Protein Alignment wupA and TNNI3

DIOPT Version :9

• Sequence 1: NP_728142.1
• Gene: wupA / 32794
• FlyBaseID: FBgn0283471
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_000354.4
• Gene: TNNI3 / 7137
• HGNCID: 11947
• Length: 210
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 67/195 - (34%)
• Similarity: 103/195 - (52%)
• Gaps: 15/195 - (7%)

  Fly    64 AEEAKKAKQAEIERKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAAEELKKEQERKA 128
            |.|.:.| .|.|.|:.:..|....|....||:|   ::..||.:|:.||.:.|.:||::|.|.:.
Human     9 AREPRPA-PAPIRRRSSNYRAYATEPHAKKKSK---ISASRKLQLKTLLLQIAKQELEREAEERR 69

  Fly   129 AERRRIIEERCGSPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYEVRKKDWEINDLNAQVN 193
            .|:.|.:..|| .|..|:.....|||::|.:.:.|:...:.:::|:|.:|.|...||.||..::.
Human    70 GEKGRALSTRC-QPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIF 133

  Fly   194 DLRGKFVKPALKKV--SKYENKFAKLQKKAAE-FNFRNQLKVVKKKEFTLEEEEKEKKP--DWSK 253
            ||||||.:|.|::|  |......|.|..:|.| .:.|..||.|||     |:.|||.:.  ||.|
Human   134 DLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKK-----EDTEKENREVGDWRK 193

  Fly   254  253
            Human   194  193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wupA	NP_728142.1	Troponin	116..233	CDD:395788	41/119 (34%)
TNNI3	NP_000354.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		11/37 (30%)
		Troponin-I_N	1..31	CDD:314500	7/22 (32%)
		Involved in binding TNC	32..79		16/49 (33%)
		Troponin	<74..177	CDD:307228	35/103 (34%)
		Involved in binding TNC and actin	129..149		9/19 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151631
Domainoid	1	1.000	75	1.000	Domainoid score	I9066
eggNOG	1	0.900	-	-		E1_KOG3977
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I5120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1566919at2759
OrthoFinder	1	1.000	-	-		FOG0000525
OrthoInspector	1	1.000	-	-		otm41636
orthoMCL	1	0.900	-	-		OOG6_105874
Panther	1	1.100	-	-	O	PTHR13738
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.760