DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wupA and tni-3

DIOPT Version :9

Sequence 1:	NP_728142.1	Gene:	wupA / 32794	FlyBaseID:	FBgn0283471	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_507250.1	Gene:	tni-3 / 180127	WormBaseID:	WBGene00006585	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	104/213 - (48%)
Similarity:	140/213 - (65%)	Gaps:	16/213 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 VKAEEAKKAKQAEIERKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAAEELKKEQER 126
            |:.:.|:||::.|:  |:||||||||||:|....||||:|||||||||.||..||||:||::|..
Worm    17 VEDDAARKAQEREL--KKAEVRKRMEEAAKKGSKKKGFLTPERKKKLRKLLMMKAAEDLKQQQML 79

  Fly   127 KAAERRRIIEER-CGSPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYEVRKKDWEINDLNA 190
            |..||::.:::| ...|...|...:|:|.:|.|:.:.|:...|.:|:|:.:.|.:.:.|||.|..
Worm    80 KEQERQKTLQQRTIPLPDVDSINDQGQLLKIYEDMFARVCALEEEKFDINFGVSQTEAEINQLTI 144

  Fly   191 QVNDLRGKFVKPALKKVSKYENKFAKLQKKAAEFNFRNQLKVVKKKEFTLEEEEKEK------KP 249
            ||||||||||||.|||||||:|||....:...:.||||.|||| |||..|:|...:|      ||
Worm   145 QVNDLRGKFVKPTLKKVSKYDNKFKSSGEVKEKSNFRNNLKVV-KKETDLDEIMAKKKGTADGKP 208

  Fly   250 DWSKGKPGDAKVKEEVEA 267
            :|||      |.|:|.||
Worm   209 EWSK------KEKKEEEA 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wupA	NP_728142.1	Troponin	116..233	CDD:395788	53/117 (45%)
tni-3	NP_507250.1	Troponin	58..188	CDD:279349	63/130 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162114
Domainoid	1	1.000	122	1.000	Domainoid score	I3484
eggNOG	1	0.900	-	-		E1_KOG3977
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H50690
Inparanoid	1	1.050	195	1.000	Inparanoid score	I2526
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29067
OrthoDB	1	1.010	-	-		D1566919at2759
OrthoFinder	1	1.000	-	-		FOG0000525
OrthoInspector	1	1.000	-	-		otm14071
orthoMCL	1	0.900	-	-		OOG6_105874
Panther	1	1.100	-	-	O	PTHR13738
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2854
SonicParanoid	1	1.000	-	-		X413
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840