DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7135 and CG16898

DIOPT Version :9

Sequence 1:	NP_573269.1	Gene:	CG7135 / 32793	FlyBaseID:	FBgn0030895	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_611452.2	Gene:	CG16898 / 37276	FlyBaseID:	FBgn0034480	Length:	407	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	111/428 - (25%)
Similarity:	175/428 - (40%)	Gaps:	56/428 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PLYLTPQFFRRTLEHGLQQLDLQVIGVQLTNLTRGGENYCSNIYRAQIKYRNAESCAMETSLIVK 73
            |.:||.::.:..|....:...|:|:.|.....|..|:||.|.:.|..::.:..:......:.|:|
  Fly     3 PNWLTEEYLQPKLRAYYKDDQLKVVKVWAKPATEKGQNYMSLMTRIHVEIQQGDGLLQNRTYIIK 67

  Fly    74 SMPDE---KQAILARLHIYNKETLFYMHIKPKLEALMWRA--VDSFSAWTLAPKHYYSTTQPEQT 133
            ....|   :..:.....:||:|...|..|.||:..|:...  ...|:|.|:.....|      :|
  Fly    68 ESLSEDCPQAKVFLEYDVYNREMDMYEFILPKMNELLQEVGLTGKFTADTIFVDREY------RT 126

  Fly   134 IILEDLCAAGYQLKCRQLGLDFDHAALVMAKLAEYHALTMVMAEREPETIV----------DRYP 188
            ||||||....|....|...||..|..|.:..||::||.::|:.:|.||.:.          |...
  Fly   127 IILEDLAQYNYVNADRVKQLDLAHTKLTLEVLAKFHAASIVVKQRHPELLTKSLFIHCFSRDNKG 191

  Fly   189 F-----GLL--HMDAINSEP-FKLLFGTQLLKLAALVGDCEGFGGITTKLYRYHEHFTERVLKAV 245
            :     |:|  .:..||.:| .|..:|.:|.|:...:.|   :|.      |..|...:.:|
  Fly   192 YTEVYEGVLSAFIRFINEQPVLKKKYGNKLQKIHENIMD---YGA------RTFEVGEQELL--- 244

  Fly   246 YPLRGNHNVLNHGDLWVNNIFFKYDAEYTVQQVKIIDFQLCFYGSLGFDINYFLNTSLELEVLRD 310
                    .|:|||.|..|..::||.....|....||||...:.|...|::.|...||..|| :|
  Fly   245 --------TLSHGDCWTTNFLYQYDDASNPQSAVAIDFQFSNFTSPVNDLHQFFTVSLRDEV-QD 300

  Fly   311 RRQELVDIYYRSLVDCLKHLPWSKELPSYEDIMDEIRKREAYGFFVAFGFFPLMSMIG--VDSED 373
            ....||:.||..|...:..|.:....||.:....:...|. :...:|..|.|::...|  |.|:.
  Fly   301 MESVLVEKYYSDLKTNVDTLSYKGIFPSLQGFQKQFESRR-FMCLLAHLFKPVIIYDGTEVSSDF 364

  Fly   374 NSLKNFHDETFARQKVQLMFEGNTRTLESLKCTLKRLD 411
            :|:....:|....||.   ...|.|.|:|....|..||
  Fly   365 SSVYKDTEEGIRFQKA---IYANERVLKSATKLLAMLD 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7135	NP_573269.1	EcKinase	43..330	CDD:281023	82/309 (27%)
CG16898	NP_611452.2	EcKinase	37..322	CDD:281023	83/311 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459186
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860