DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7135 and CG33301

DIOPT Version :9

Sequence 1:	NP_573269.1	Gene:	CG7135 / 32793	FlyBaseID:	FBgn0030895	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001285793.1	Gene:	CG33301 / 2768917	FlyBaseID:	FBgn0053301	Length:	407	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	117/433 - (27%)
Similarity:	183/433 - (42%)	Gaps:	55/433 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PLYLTPQFFRRTLEHGLQQLDLQVIGVQLTNLTRGGENYCSNIYRAQIKYRNAESCAMETSLIVK 73
            |.:||..:.:..|....|...|||:.:.....|..|||:...:.|..:.|:..:...:..:.||
  Fly     3 PTWLTAAYLQPRLRAYCQDDRLQVLRIWAKPATGKGENFVGVMTRIYVDYQLGDGSVVNKTYIV- 66

  Fly    74 SMPDEKQAILARL---------HIYNKETLFYMHIKPKLEALMWRA-VD-SFSAWTLAPKHYYST 127
                 |||:.|.:         .:|.:|...|..|.|||:.|:..| :| ..:|..:.....|:
  Fly    67 -----KQALSAEVPQAEVFFEYELYTREMDMYEFILPKLKELLQEAGLDQKLTADAITVDREYN- 125

  Fly   128 TQPEQTIILEDLCAAGYQLKCRQLGLDFDHAALVMAKLAEYHALTMVMAEREPETIVDRYPFGLL 192
                 |:|||||....:....|...||..|..|.:..||::||.::|:.||.|..:...:   ..
  Fly   126 -----TMILEDLAPYKFVNADRVKQLDMAHTELTLEMLAKFHAASIVLQERHPNLLTKCF---YT 182

  Fly   193 HMDAINSEPFKLLF------------GTQLLKLAALVGDCEGFGGITTKLYRYHEHFTERVLKAV 245
            |..:.:.:.:.::|            |...||        |.:|   .||::...|..|...:|.
  Fly   183 HFFSRDKKAYSVVFAGLFKAFLRFIDGQPNLK--------EAYG---DKLHKLRTHIMEYGARAY 236

  Fly   246 YPLRGNHNVLNHGDLWVNNIFFKYDAEYTVQQVKIIDFQLCFYGSLGFDINYFLNTSLELEVLRD 310
            .....:...|||||.|..||.|:||.....:.|..||||.....|...|::||..|||..|| .|
  Fly   237 DVGESDLKTLNHGDCWTTNIMFQYDDAGEPRSVVAIDFQFSNCTSPTIDLHYFFTTSLREEV-GD 300

  Fly   311 RRQELVDIYYRSLVDCLKHLPWSKELPSYEDIMDEIRKREAYGFFVAFGFFPLMSMIGVD--SED 373
            :..|||:.:|::|...|:...:...||:.::...:..:|. :...:|..|.|.|...|.:  |:.
  Fly   301 KESELVEHHYKALKANLEKFSYKGSLPTLQEYRLQFERRR-FMSLLAHMFKPCMIYNGSEETSDF 364

  Fly   374 NSLKNFHDETFARQKVQLMFEGNTRTLESLKCTL--KRLDELK 414
            :||.....|....||.....|...|:...|...|  |.|.||:
  Fly   365 SSLYAESPEGLRYQKSVYASEAVIRSATKLLAILDAKGLLELQ 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7135	NP_573269.1	EcKinase	43..330	CDD:281023	86/309 (28%)
CG33301	NP_001285793.1	EcKinase	37..322	CDD:281023	86/311 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459185
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860