DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Taf8 and taf3

DIOPT Version :9

Sequence 1:	NP_523397.1	Gene:	Taf8 / 32792	FlyBaseID:	FBgn0022724	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001036209.1	Gene:	taf3 / 334474	ZFINID:	ZDB-GENE-030131-6406	Length:	898	Species:	Danio rerio

Alignment Length:	340	Identity:	84/340 - (24%)
Similarity:	130/340 - (38%)	Gaps:	81/340 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RRILNKVVSQLLLDKGAGQASNHSLETLTQMLQALIWEIGNSAHNYCELSGRTMPTVGDVSLALI 80
            |.:|...|:|:....|.......:.:.|:.:|:..:.::..|.|.|.||.|||.|.:.||..|..
Zfish     7 RSLLRVSVAQMCQAVGWDAVQLSACDLLSDVLERYVQQLAKSCHRYSELYGRTDPGLSDVDQAFG 71

  Fly    81 NMGISISNLDPYMRKETHVPIPLPPQQTQQRPL---SLLQ---AG--------IKAPHPHYVPSY 131
            .:|:||:.|:.|:....  ||.. ||...|.|:   |:||   ||        ::.....|:|.|
Zfish    72 FLGVSIAELEDYVNNVE--PIGY-PQTIPQFPISKSSVLQFPAAGFDTDARDALRGERRDYIPEY 133

  Fly   132 FPPMPDPHAYIRTPTHKQPV-----TEYEAIR-----EKAACQKRDIEKALTKFLCKTTETNNLF 186
            |||:.   :.......::||     |..||::     |:...::.:.|..|::...::.....|.
Zfish   134 FPPLV---SLQEDEEEEEPVPADMGTSAEAMQVSMGEEEDGEEEENDENWLSRHDGQSPRPEGLL 195

  Fly   187 PTEDNMFPLIACKPAFPPYAAALNPTDQVFDFEELEYHYLVANRTEDEPSKDDGEEGDSEN-EEM 250
            |....  |.::.||...|                 |:.|        ||.    |...|.| :.|
Zfish   196 PAAKR--PRLSTKPGVSP-----------------EWSY--------EPR----EPLSSLNSQHM 229

  Fly   251 DGDKSKEEKPEL---DIKPNSNTNKAILENPNIDNPYLRAATLPKRSKNCPTPGTMPSRSLATTA 312
            ....|....|||   .:.|.:..:|..|.:|:           |.|.||     ..|.|..|...
Zfish   230 PHSPSPPLSPELPRPPVAPPTPGHKPKLPSPS-----------PARQKN-----KSPKRGGAAPT 278

  Fly   313 PTIRTPSTLEITKTN 327
            ..:..|.||...|||
Zfish   279 GVLGRPLTLTPPKTN 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf8	NP_523397.1	BTP	15..88	CDD:128846	22/71 (31%)
Taf8	NP_523397.1	TAF8	126..179	CDD:176263	14/62 (23%)
taf3	NP_001036209.1	BTP	5..79	CDD:128846	22/71 (31%)
taf3	NP_001036209.1	PHD_TAF3	836..881	CDD:276997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1475
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840