DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Taf8 and taf-3

DIOPT Version :9

Sequence 1:	NP_523397.1	Gene:	Taf8 / 32792	FlyBaseID:	FBgn0022724	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001257272.1	Gene:	taf-3 / 181704	WormBaseID:	WBGene00006384	Length:	1007	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	86/417 - (20%)
Similarity:	144/417 - (34%)	Gaps:	121/417 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKVEAVTVSNVDPYRRILNKVVSQLLLDKGAGQASNHSLETLTQMLQALIWEIGNSAHNYCELS 65
            ||:.::::..:...|:  |......:|.|.|....:..:...|..:|::.|.|..:|...:.||:
Worm     1 MEESQSLSAHDFAVYK--LQDTCKSILRDFGFTSVAQSANSKLAALLRSKINEYAHSTRAFMELA 63

  Fly    66 GRTMPTVGDVSLALINMGISISNLDPYMRKETH-----VP-IPLPPQQTQQRPLSLLQAGIKAPH 124
            |||.|...||..|..:..:|:.:|..|.::...     :| ||:|.|:..:...:..:: :..|.
Worm    64 GRTKPVTNDVIAAFKHQKVSLPDLKDYAKQVKSEMLHALPVIPVPDQEIAKSDDNFFRS-MYGPK 127

  Fly   125 P---------HYVPSYFPPM-------------PDP------------------------HAYIR 143
            |         .::||:|..:             ||.                        :.|.|
Worm   128 PSEKELEERREHIPSHFRALHPEWIEEENKEKPPDDTGTRKVVKSAEEREQDEFNKLKRINTYRR 192

  Fly   144 --TPTHKQPVTEYE--AIREKAACQKRDIEK-----------ALTKF---------LCKTTETNN 184
              .|..:|...|.|  ...|.|..:||:.|:           .|..|         ..|..|.|.
Worm   193 NENPEVQQAREEKERREAEEAAYAKKRNHERFKKGITALPGSTLPNFEDMNFVETGFFKDFEENK 257

  Fly   185 LFPTEDNMFPLIACK--PAFPPYAAALNPTDQVFDFEELEYHYLVANRTEDEPSKDDGEEGDSEN 247
            ....|..:....|.|  |..||  ..:|.....|..:.:......:......||..:..|...:|
Worm   258 RLEAERRLQVQNASKVAPTLPP--PVVNKPLPSFSTDSVSASSSASASIMASPSLGEMAEAFLKN 320

  Fly   248 E-EMD-----GDKSKEEKPELD-----------IKPNSNTNKAILENPNIDNPYLRAATLPKRSK 295
            : .||     |...:.:.|..|           :|||              .|||:   ||....
Worm   321 KIFMDTINAYGKSFEHKSPFKDDSGPAFRLSELVKPN--------------KPYLK---LPGTGS 368

  Fly   296 NCPTPGTMPSRSLATTAPTIRTPSTLE 322
            |   ||:.|| |...::.:|.||:.::
Worm   369 N---PGSAPS-SRPGSSMSIGTPTKVK 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf8	NP_523397.1	BTP	15..88	CDD:128846	20/72 (28%)
Taf8	NP_523397.1	TAF8	126..179	CDD:176263	18/113 (16%)
taf-3	NP_001257272.1	BTP	11..86	CDD:128846	20/76 (26%)
taf-3	NP_001257272.1	PHD_TAF3	931..976	CDD:276997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1475
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940