Protein Alignment RhoGAP16F and RGA1

DIOPT Version :9

• Sequence 1: NP_001285400.1
• Gene: RhoGAP16F / 32790
• FlyBaseID: FBgn0030893
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_014770.1
• Gene: RGA1 / 854294
• SGDID: S000005653
• Length: 1007
• Species: Saccharomyces cerevisiae
• Alignment Length: 644
• Identity: 124/644 - (19%)
• Similarity: 216/644 - (33%)
• Gaps: 238/644 - (36%)

  Fly     2 QTTTSQRPVTP------GTPDSAHIVIGAAGFVAHERRQPGKTLMNCFRDRSTTSSSSSQAQHAY 60
            :|...||||..      ..||.|.        |..|:.:......|..:.|..:.|.|.:::...
Yeast   371 ETNALQRPVVEVVKEDRSVPDLAG--------VQQEQAEKYSYSNNSGKGRKISRSLSRRSKDLM 427

  Fly    61 VRGHSVTSSTLFRLEGSGGSNCTLDKAGKQDTGRPEAVVLLRELKT---RPNKLALLKSSSSKDL 122
            :...|       |..|...||..|..|.|..:.|.:.::...:..|   .||     .:|:|.|:
Yeast   428 INLKS-------RATGKQDSNVKLSPASKVTSRRSQDLMRDNDSHTGLDTPN-----SNSTSLDI 480

  Fly   123 T---------RLFLDDSTNTAVLVSNTSIDVCSSNSSSGGSPAVGRSKSGR-------------- 164
            .         :.|.|:.|........|:::...::|....||.....:|..
Yeast   481 LVNNQKSLNYKRFTDNGTLRVTSGKETALEEQKNHSFKSPSPIDHLLQSPATPSNVSMYRTPPLD 545

  Fly   165 -----DRRNGLECCSSCSKR------W--------------HDLKQRMH---------TLEQDLL 195
                 |||||    ||.|.:      |              .:.|:.::         :|:::::
Yeast   546 SSLTFDRRNG----SSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPSLDKEIV 606

  Fly   196 VQTTY-------SQELEQKVGEMSRQLTELLQERDRER--------DKDK--------------- 230
            ....|       .:|||.:..|:.:::||:...::..|        :|:|
Yeast   607 TAEHYLKQLKINLKELESQREELMKEITEMKSMKEALRRHIESYNSEKNKLYLDSNELSNNPPMI 671

  Fly   231 -----------ARFAAAGGVA-------------------------------------------A 241
                       ...|.|..||                                           |
Yeast   672 NEISLGESPPVKHVATASSVARSSVKPKFWKFFSSAKPQTEQSIQGVSTNNTNSIVKSAPVLLSA 736

  Fly   242 PGKRTAHGSPNVRPS-----------RLVAWMNLSNWFKSRPSVETLREQRIFFDEPCFDTELEM 295
            |...:..|...:.|.           |||...|.:|..:|:...|.|....::..        .:
Yeast   737 PSSGSNSGRLEISPPVLQNPNEFSDVRLVPIENDANMGQSKDGEEYLDGSNLYGS--------SL 793

  Fly   296 VLK-HDQHRTVPRIVVDCCDLIE--QKYRRSTQPIEGIYRQCGDYNKIQTLRFSIDA-NDYDSLR 356
            |.: :.::..:|.|:..|.|.||  ::..||    |||||:.|....|:.:.....| ....:..
Yeast   794 VARCNYENNEIPMILSVCIDFIESDEENMRS----EGIYRKSGSQLVIEEIEKQFSAWKVQQNTE 854

  Fly   357 QPDV----DIHTLTGVLKLFLR---------EIKSPLVRVNEAK------TFIGQPNQWLL---- 398
            .|::    |::.:|||||.:||         :|..||:|:.::|      .|:|  .:..|
Yeast   855 TPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVG--GKLSLEAKN 917

  Fly   399 --TDLSAKLDSLKRLIRSLPESN----RDTMDYI-----FGHFNRITKVPLQQISAETL 446
              |.:|:| .:||.::..||..:    |...::|     :.|:||:|...|..:.|..|
Yeast   918 SDTYMSSK-SALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGL 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	49/178 (28%)
RGA1	NP_014770.1	LIM1_Rga	13..67	CDD:188780
		LIM2_Rga	70..123	CDD:188781
		Smc	<569..>673	CDD:224117	12/103 (12%)
		RhoGAP	803..1002	CDD:214618	49/180 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100