DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP16F and Arhgap15

DIOPT Version :9

Sequence 1:	NP_001285400.1	Gene:	RhoGAP16F / 32790	FlyBaseID:	FBgn0030893	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_722542.2	Gene:	Arhgap15 / 76117	MGIID:	1923367	Length:	481	Species:	Mus musculus

Alignment Length:	209	Identity:	64/209 - (30%)
Similarity:	106/209 - (50%)	Gaps:	19/209 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 LSNWFKSRPSVETLREQRIFFDEPCFDTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIE 328
            |..:...|||::||:|:.:..|: .|.:.|..|.:. :|.|||..|..|.:.:|::    ...::
Mouse   261 LKKFISRRPSLKTLQEKGLIKDQ-IFGSHLHTVCER-EHSTVPWFVKQCIEAVEKR----GLDVD 319

  Fly   329 GIYRQCGDYNKIQTLRFSIDANDYDSLRQPD---VDIHTLTGVLKLFLREIKSPLVRVNEAKTFI 390
            ||||..|:...||.|||.:  |..:.|...|   .|||.:||.||:|.||:..||...:..:.|:
Mouse   320 GIYRVSGNLATIQKLRFIV--NQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFV 382

  Fly   391 GQPNQWLLTDLSAKLDSLKRLIRSLPESNRDTMDYIFGHFNRI-TKVPLQQISAETLSISVTPSI 454
            ....:   .|.:.|:::::.|::.||..|.|||..:|.|..:| .|.....:|.::|.|...|::
Mouse   383 EAIKK---QDSNEKIETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTL 444

  Fly   455 FHTVPQ----GVHM 464
            .....:    .|||
Mouse   445 LRAENESGNVAVHM 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	50/167 (30%)
Arhgap15	NP_722542.2	PH	88..196	CDD:278594
		PH_ARHGAP9-like	89..198	CDD:270053
		RhoGAP_ARHGAP27_15_12_9	285..471	CDD:239868	56/184 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4483
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000816
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.860