Protein Alignment RhoGAP16F and arhgap27l

DIOPT Version :9

• Sequence 1: NP_001285400.1
• Gene: RhoGAP16F / 32790
• FlyBaseID: FBgn0030893
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_694888.4
• Gene: arhgap27l / 566523
• ZFINID: ZDB-GENE-120406-11
• Length: 1014
• Species: Danio rerio
• Alignment Length: 551
• Identity: 128/551 - (23%)
• Similarity: 222/551 - (40%)
• Gaps: 160/551 - (29%)

  Fly     2 QTTTSQRPVTPGTPDSAHIVIGAAGFVAHERRQPGKTLMNCFR---------------------- 44
            |.|..:..|.||.|.:.:.|           .|.|..::|.:|
Zfish   537 QWTLPEASVPPGQPMNGNGV-----------EQDGPPVLNNWRYTQFNISQEDLKFSPSHRRIAS 590

  Fly    45 DRSTTSSSSS---QAQH---AYVRGHSVTS-STLFRLEGSGGSNCTLDKAGKQDTGRPEAVVLLR 102
            |.::.:|||.   ::||   .:.|..:::| ||     .|...:.:|:|||           :|.
Zfish   591 DNASDASSSGNSPESQHYDKKFRRRRNLSSYST-----DSHSHHSSLEKAG-----------ILN 639

  Fly   103 ELKTRPNKLALLKSSSSK-----DLTRLFLDD--------STNTAVLVSNTSIDVCSSNSSSGGS 154
            :.|...|...|.|:.:..     |....|..|        |:.|..:|...::::       .|:
Zfish   640 KTKVAENGKRLRKNWAQSWTVLHDGVLTFHKDPKFAPAGMSSKTNQIVPEYTVEL-------KGA 697

  Fly   155 PAVGRSKSGRDRRNGLECCSSCSKRWHDLKQRMHTLE--------------QDLLVQTTYSQELE 205
            .....||....::|.||           ||.| |..|              |.:::.|.   :|.
Zfish   698 TLSWASKEKSSKKNVLE-----------LKTR-HGSEYLIQYDTDSIIQDWQKIILDTI---KLL 747

  Fly   206 QKVGEMSRQLTELLQER-----DRERDKDKARFAAAGGVAAPGKRTAHGSPNVRPSRLVAWMNLS 265
            .:.|..|....|.:.|:     |:|:..:.||.::...:.....|       ||       ..|.
Zfish   748 HEHGHNSEDEAEDVPEKSPLPADKEKKPEAARLSSTSSIDTDQGR-------VR-------TKLR 798

  Fly   266 NWFKSRPSVETLREQRIFFDEPCFDTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGI 330
            .:.:.||::::::|:. :..|..|...|: .|.|.::.|||:.|..|...:|::..:    |:||
Zfish   799 KFLQRRPTLQSVKEKG-YIKENVFGCHLD-TLCHRENTTVPKFVEKCIRSVEKRGLK----IDGI 857

  Fly   331 YRQCGDYNKIQTLRFSIDANDYDSLRQPDVD--------IHTLTGVLKLFLREIKSPLVRVNEAK 387
            ||..|:...||.||:..|       .:.|:|        ||.:||.|||||||:..||...:...
Zfish   858 YRVSGNLAVIQKLRYKAD-------HEEDLDLEDGQWEEIHVITGALKLFLRELPEPLFPFSFFD 915

  Fly   388 TFIGQPNQWLLTDLSAKLDSLKRLIRSLPESNRDTMDYIFGHFNRITK-VPLQQISAETLSISVT 451
            .||....   ::|.|.|:..::.|:|:||..|.|||:.:|.|..::.: ..:.::|.::.:|...
Zfish   916 KFIAAIQ---ISDYSQKVSYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFG 977

  Fly   452 PSIFHTVPQ-----GVHM----QDIQQLLRE 473
            |::..  ||     .:||    |.::.:|.|
Zfish   978 PTLLR--PQEESNITMHMVFQNQIVELVLNE 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	55/186 (30%)
arhgap27l	XP_694888.4	SH3_ARHGAP27	15..71	CDD:213002
		WW	340..368	CDD:278809
		WW	394..422	CDD:278809
		PH	632..745	CDD:278594	28/145 (19%)
		PH_ARHGAP9-like	633..744	CDD:270053	26/140 (19%)
		RhoGAP_ARHGAP27_15_12_9	821..1006	CDD:239868	60/201 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592294
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000816
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1079
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930