Protein Alignment RhoGAP16F and arhgap27l

DIOPT Version :10

• Sequence 1: NP_001285400.1
• Gene: RhoGAP16F / 32790
• FlyBaseID: FBgn0030893
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_694888.5
• Gene: arhgap27l / 566523
• ZFINID: ZDB-GENE-120406-11
• Length: 1014
• Species: Danio rerio
• Alignment Length: 551
• Identity: 128/551 - (23%)
• Similarity: 222/551 - (40%)
• Gaps: 160/551 - (29%)

  Fly     2 QTTTSQRPVTPGTPDSAHIVIGAAGFVAHERRQPGKTLMNCFR---------------------- 44
            |.|..:..|.||.|.:.:.|           .|.|..::|.:|
Zfish   537 QWTLPEALVPPGQPMNGNGV-----------EQDGPPVLNNWRYTQFNISQEDLKFSPSHRRIAS 590

  Fly    45 DRSTTSSSSS---QAQH---AYVRGHSVTS-STLFRLEGSGGSNCTLDKAGKQDTGRPEAVVLLR 102
            |.::.:|||.   ::||   .:.|..:::| ||     .|...:.:|:|||           :|.
Zfish   591 DNASDASSSGNSPESQHYDKKFRRRRNLSSYST-----DSHSHHSSLEKAG-----------ILN 639

  Fly   103 ELKTRPNKLALLKSSSSK-----DLTRLFLDD--------STNTAVLVSNTSIDVCSSNSSSGGS 154
            :.|...|...|.|:.:..     |....|..|        |:.|..:|...::::       .|:
Zfish   640 KTKVAENGKRLRKNWAQSWTVLHDGVLTFHKDPKFAPAGMSSKTNQIVPEYTVEL-------KGA 697

  Fly   155 PAVGRSKSGRDRRNGLECCSSCSKRWHDLKQRMHTLE--------------QDLLVQTTYSQELE 205
            .....||....::|.||           ||.| |..|              |.:::.|.   :|.
Zfish   698 TLSWASKEKSSKKNVLE-----------LKTR-HGSEYLIQYDTDSIIQDWQKIILDTI---KLL 747

  Fly   206 QKVGEMSRQLTELLQER-----DRERDKDKARFAAAGGVAAPGKRTAHGSPNVRPSRLVAWMNLS 265
            .:.|..|....|.:.|:     |:|:..:.||.::...:.....|       ||       ..|.
Zfish   748 HEHGHNSEDEAEDVPEKSPLPADKEKKPEAARLSSTSSIDTDQGR-------VR-------TKLR 798

  Fly   266 NWFKSRPSVETLREQRIFFDEPCFDTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGI 330
            .:.:.||::::::|:. :..|..|...|: .|.|.::.|||:.|..|...:|::..:    |:||
Zfish   799 KFLQRRPTLQSVKEKG-YIKENVFGCHLD-TLCHRENTTVPKFVEKCIRSVEKRGLK----IDGI 857

  Fly   331 YRQCGDYNKIQTLRFSIDANDYDSLRQPDVD--------IHTLTGVLKLFLREIKSPLVRVNEAK 387
            ||..|:...||.||:..|       .:.|:|        ||.:||.|||||||:..||...:...
Zfish   858 YRVSGNLAVIQKLRYKAD-------HEEDLDLEDGQWEEIHVITGALKLFLRELPEPLFPFSFFD 915

  Fly   388 TFIGQPNQWLLTDLSAKLDSLKRLIRSLPESNRDTMDYIFGHFNRITK-VPLQQISAETLSISVT 451
            .||....   ::|.|.|:..::.|:|:||..|.|||:.:|.|..::.: ..:.::|.::.:|...
Zfish   916 KFIAAIQ---ISDYSQKVSYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFG 977

  Fly   452 PSIFHTVPQ-----GVHM----QDIQQLLRE 473
            |::..  ||     .:||    |.::.:|.|
Zfish   978 PTLLR--PQEESNITMHMVFQNQIVELVLNE 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	55/186 (30%)
arhgap27l	XP_694888.5	None