Protein Alignment RhoGAP16F and arhgap12b

DIOPT Version :10

• Sequence 1: NP_001285400.1
• Gene: RhoGAP16F / 32790
• FlyBaseID: FBgn0030893
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_073773592.1
• Gene: arhgap12b / 393848
• ZFINID: ZDB-GENE-040426-1727
• Length: 893
• Species: Danio rerio
• Alignment Length: 471
• Identity: 111/471 - (23%)
• Similarity: 195/471 - (41%)
• Gaps: 122/471 - (25%)

  Fly    68 SSTLF-RLEGSG--GSNCTLDKAGKQDTGRPEAVVLL-----RELKTRPNKLALLKSSSSKDLTR 124
            ||.|| :.:|||  .|.|       .:...||.::.|     |.:|.||
Zfish   501 SSLLFAKGQGSGTSWSYC-------HNGSFPELLLSLLSNWKRSIKPRP---------------- 542

  Fly   125 LFLDDSTNTAVLVSNTSIDVC--SSNSSSGGSPAVGRSKSGRDRRNG-LECCS---SCSKRWHDL 183
                       .||.|.   |  :..||.||:.:  :.:...|.|.| :|..|   |..|...:|
Zfish   543 -----------AVSYTH---CRRARASSFGGNQS--KPEFTVDLRGGSVEWASKEKSSKKHVIEL 591

  Fly   184 KQRMHTLEQDLLVQTTYSQELEQKVGEMSRQLTELL---------------------QERDRE-- 225
            |.|:.|   :||:|:    |::..:.:..|.|:|.:                     ::.|:|
Zfish   592 KTRVGT---ELLIQS----EIDSVINDWFRALSETINTHAWESDEAIEEDMPESPGSEKHDKEKD 649

  Fly   226 -RDKDKARFAAAGGVAAPGKRTAHGSPNVRPSRLVAWMNLSNWFKSRPSVETLREQRIFFDEPCF 289
             ||..|.|..         |.::..|...:.:|    :.|..:...||:::.:|::....|: .|
Zfish   650 PRDSKKNRVV---------KNSSMESSEQKKTR----VKLKKFLTRRPTLQAVRDKGYIKDQ-VF 700

  Fly   290 DTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGIYRQCGDYNKIQTLRFSIDANDYDS 354
            ...|..:.:. :..:||..|..|.:.:|    .:...::|:||..|:...||.|||:::.::..:
Zfish   701 GCSLTALCQR-EGTSVPNFVKMCIEHVE----NTGLNVDGLYRVSGNLAVIQKLRFAVNHDEKVN 760

  Fly   355 LRQPD-VDIHTLTGVLKLFLREIKSPLVRVNEAKTFIGQPNQWLLTDLSAKLDSLKRLIRSLPES 418
            |.... .|||..||.||:..||:..||........|:.....   :|...::.|:|.||:.||:.
Zfish   761 LDDSKWEDIHVTTGALKMLFRELPEPLFTYASFNDFVEAIKN---SDYKQRVQSIKDLIKQLPKP 822

  Fly   419 NRDTMDYIFGHFNR-ITKVPLQQISAETLSISVTPSI----FHTVPQGVHMQDIQQLLREGETLA 478
            |::||..:|.|..| |....:.:::.::::|...|::    ..|....|||....|::.
Zfish   823 NQETMKVLFKHLKRVIDHGEVNRMTTQSVAIVFGPTLLRPEIETGNMAVHMVYQNQIVE------ 881

  Fly   479 DCVKLMIEYQGRIFDR 494
               .:::||: .||.|
Zfish   882 ---LILLEYE-NIFGR 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	47/186 (25%)
arhgap12b	XP_073773592.1	None