Protein Alignment RhoGAP16F and Arhgap9

DIOPT Version :9

• Sequence 1: NP_001285400.1
• Gene: RhoGAP16F / 32790
• FlyBaseID: FBgn0030893
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_006241526.1
• Gene: Arhgap9 / 362893
• RGDID: 1305342
• Length: 642
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 145/624 - (23%)
• Similarity: 220/624 - (35%)
• Gaps: 210/624 - (33%)

  Fly    13 GTPDSAHIVIGAAGFVAHERRQPGKTLMNCFRDRSTTSSSS------------------SQAQHA 59
            |.|.|:..:...|.:|..|.       ::|.....:|.:||                  || :|.
  Rat    68 GAPPSSRPIFVPAAYVTEES-------VSCHNPAGSTHNSSLWTPGTKLYRGSLEDLYLSQ-EHQ 124

  Fly    60 YVRG------HSVTSSTLFRLEGSGGSNCTLD--KAG------KQDTGRPEAVVLLRELKTRPNK 110
            .|.|      |.:..|    :..:....|:|.  |.|      .||..|.||.....:..:..:.
  Rat   125 VVSGQPPHCSHKMCRS----VSMANVKLCSLKPFKEGPQERFLSQDCWRTEASAAAVKSGSMEHT 185

  Fly   111 LALLKSS---------SSKDLTRLF--------------------LDDSTNTA------------ 134
            .||::.|         :::||..|.                    |.:.|..|
  Rat   186 EALIRDSNPLQHQEWLNAQDLPSLSQSIPWPDVSEQPCPHEERSGLLNMTKIAQGGRKLRKSWGP 250

  Fly   135 ---VLVSNTSI------DVCSSNSSSGGSPAVGRSKSGRDRRNGLECCSSCSKRWHDLKQRMHTL 190
               ||..|:.:      ..|:  .|.|.:||..|.:|..|.| |....|.     ..|..|.:.|
  Rat   251 AWVVLTGNSLVFYRERPPQCA--PSQGWAPAGSRPESSVDLR-GAALASG-----RQLSSRRNVL 307

  Fly   191 E------QDLLVQTTYSQELEQKVGEMS-RQLTELLQERDRERDKDKARFAAAG----------- 237
            .      .:.|:|:  .:|.|.:....: |.:.|.|..||||...: .|.:.:|
  Rat   308 HIRTVPGHEFLLQS--DEETELRAWHRALRAVIERLVRRDRENPLE-LRLSGSGPAELAELSGGE 369

  Fly   238 ----------------GVAAPGKRTAHGSP---NVRP--SRLVAWMNLSNWFKSRPSVETLREQR 281
                            |......|.|.|:.   .||.  .||:|         .||::::|:|:.
  Rat   370 DDELESEPVSKSLMRLGSRRTSSRCAEGTDQKNRVRNKLKRLIA---------KRPTLQSLQERG 425

  Fly   282 IFFDEPCFDTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGIYRQCGDYNKIQTLRFS 346
            :|.|: .|..:||.:.:.:.. |||..|..|.:.:::|    ...::||||..|:...:|.|||.
  Rat   426 LFRDQ-VFGCQLESLCQREGD-TVPSFVRLCVEAVDKK----GLDVDGIYRVSGNLAVVQKLRFL 484

  Fly   347 IDAN---------------------DYDSLRQPDVDIHTLTGVLKLFLREIKSPLVRVNEAKTF- 389
            :|..                     |.||....  |||.:||.||||.||:..|||.......|
  Rat   485 VDRERAVTSDGRYMFPEQPGQEGKLDLDSAEWD--DIHVITGALKLFFRELPQPLVPALLLPHFR 547

  Fly   390 ----IGQPNQWLLTDLSAKLDSLKRLIRSLPESNRDTMDYIFGHFNR-ITKVPLQQISAETLSIS 449
                :.:|...        |..:::||.|||..|.||:.||..|..| |......:::|..|.|.
  Rat   548 DALELSEPEHC--------LSKIQKLIDSLPRPNHDTLQYILEHLCRVIAHSDKNRMTAHNLGIV 604

  Fly   450 VTPSIF-----------HTVPQGVHMQDIQQLLREGETL 477
            ..|::|           |.|..|   |.||.:|....:|
  Rat   605 FGPTLFRPEQEASDMAAHVVYPG---QLIQLMLNNFASL 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	60/210 (29%)
Arhgap9	XP_006241526.1	SH3	27..82	CDD:302595	4/13 (31%)
		PH_ARHGAP9-like	227..340	CDD:270053	25/122 (20%)
		PH	241..339	CDD:278594	22/107 (21%)
		RhoGAP_ARHGAP27_15_12_9	432..636	CDD:239868	64/221 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000816
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1079
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.000