Protein Alignment RhoGAP16F and Syde2

DIOPT Version :10

• Sequence 1: NP_001285400.1
• Gene: RhoGAP16F / 32790
• FlyBaseID: FBgn0030893
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_017446301.2
• Gene: Syde2 / 308021
• RGDID: 1564206
• Length: 1281
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 132/655 - (20%)
• Similarity: 221/655 - (33%)
• Gaps: 187/655 - (28%)

  Fly    34 QPGKTLMNCFRDRSTTSSSSSQAQHAYVRGHSVTSST----LFRLEGSGGSNCTLDKAGKQDTGR 94
            ||.:..:......|.|:..|...:.|:. |..:..||    |..||....|...:.|........
  Rat   545 QPCRQRLGHRTQESLTAEDSPGLKSAFT-GPGILVSTNRTELRALEPPSPSPSPVKKGSSITWSL 608

  Fly    95 PEAVVLLRELKTRPNKLALLKSSSSK-----------------DLTRLFLDDSTNTAVL------ 136
            |:.:...|.::....|:..|...|.|                 .|::.:..:...:.:|
  Rat   609 PDKIKSPRTVRKLSMKMKRLPEFSRKRGARGALHYTNSPDRTPPLSKWYYGEGPQSVLLPSGNPA 673

  Fly   137 ---VSNTSID--VCSSNS------------------SSGGSPAV--GRSKSGRDRR--NGLECC- 173
               :|...:|  |.|.:|                  |.|.||.:  ..||.|.:.|  .|.|..
  Rat   674 SNVISRYHLDTTVSSQHSYQKKPLGSSRYPCKGGYLSDGDSPELRTRSSKHGSEHRLGKGREAVP 738

  Fly   174 SSCSKRWHDLKQRMHTLEQD----------LLVQTTYSQE------LEQK-------VGEMSRQL 215
            |.|||...|:....|....|          |:....|..|      ::.|       |..:::..
  Rat   739 SGCSKNEIDVGAFRHYSFSDQPKCSQYISGLMSVHFYGAEGLKPPRIDSKDVFCAIQVDSVNKAR 803

  Fly   216 TELLQERDRERDKD-------------------------KARFAAAGGVAAPG----KRTAHGSP 251
            |.||..|....|.|                         :.|....|.|..|.    .||...:.
  Rat   804 TALLTCRTTFLDLDHTFNIEIENAQHLKLVVFSWEPTPRRNRVCCHGTVVLPALFRVTRTHQLAV 868

  Fly   252 NVRPSRLV--------AWMN-LSNWFKSRPSVETLREQRIFFDEPCFDTELEMVL-KHDQHRTVP 306
            .:.|..|:        .|.| |....|:|.||             .|..:::.|: |.:....||
  Rat   869 KLEPRGLIYVKVTLMEQWENSLHGLDKNRESV-------------MFGVDIQKVVEKENAGLMVP 920

  Fly   307 RIVVDCCDLIEQKYRRSTQPIEGIYRQCGDYNKIQTLR--FSIDANDYDSLRQPDVDIHTLTGVL 369
            .::..|...||   :|..| :.|:||.||.....:.||  |..|:...........||:.:||||
  Rat   921 LLIQKCIMEIE---KRGCQ-VVGLYRLCGSAAVKKELREAFEKDSKTVGLCEDQYPDINVITGVL 981

  Fly   370 KLFLREIKSPLVRVNEAKTFI-------------GQPNQWLLTDLSAKLDSLKRLIRSLPESNRD 421
            |.:|||:.|||:.....:..:             |..|:  .:|....:|    |:..||:..:.
  Rat   982 KDYLRELPSPLITKQLYQAVLDAMVKSPLKMSSNGCENE--SSDSRFTVD----LLNCLPDVEKA 1040

  Fly   422 TMDYIFGHFNRITKV-PLQQISAETLSISVTPSIFHTVPQ-GVHMQDIQQLLREGETLADCVKL- 483
            |:..:..|...:... .:.:::.:.|::...|.:.:...: ..|.   .::..:.|.||..:..
  Rat  1041 TLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLNQRQETSTHN---NRVFSDSEELASALDFK 1102

  Fly   484 ----MIEYQGRIF-----------DRLRLIQTAHL--LCR-----CVERFANHSKSEILNPKP-- 524
                ::.|..:::           |.|.|.|::.|  |.|     ||...:....|.:|.|:.
  Rat  1103 KHIEVLHYLLQLWPVQCLTVKEPRDSLCLEQSSSLNYLRRKKERPCVLNLSGSDSSGVLRPRQAR 1167

  Fly   525 -NTPL 528
             ::||
  Rat  1168 LDSPL 1172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	43/202 (21%)
Syde2	XP_017446301.2	PHA03247	<115..324	CDD:223021
		C2	767..882	CDD:472691	19/114 (17%)
		RhoGAP	902..1116	CDD:470621	48/226 (21%)