DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP16F and Arhgap15

DIOPT Version :9

Sequence 1:	NP_001285400.1	Gene:	RhoGAP16F / 32790	FlyBaseID:	FBgn0030893	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001013939.1	Gene:	Arhgap15 / 295635	RGDID:	1359304	Length:	482	Species:	Rattus norvegicus

Alignment Length:	209	Identity:	70/209 - (33%)
Similarity:	109/209 - (52%)	Gaps:	19/209 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 LSNWFKSRPSVETLREQRIFFDEPCFDTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIE 328
            |..:...|||::||:|:.|..|: .|.:.|..|.:. :|.|||..|..|.:.:|   :|..: ::
  Rat   262 LKKFISRRPSLKTLQEKGIIKDQ-IFGSHLHTVCER-EHSTVPWFVKQCIEAVE---KRGLE-VD 320

  Fly   329 GIYRQCGDYNKIQTLRFSIDANDYDSLRQPD---VDIHTLTGVLKLFLREIKSPLVRVNEAKTFI 390
            ||||..|:...||.|||.:  |..:.|...|   .|||.:||.||:|.||:..||...:..:.|:
  Rat   321 GIYRVSGNLATIQKLRFIV--NQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFV 383

  Fly   391 GQPNQWLLTDLSAKLDSLKRLIRSLPESNRDTMDYIFGHFNRITKVPLQQI-SAETLSISVTPSI 454
            ....:   .|..||::::|.|::|||..|.|||..:|||..:|.....|.: |.::|.|...|::
  Rat   384 EAIKK---QDSDAKIETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQNLMSTQSLGIVFGPTL 445

  Fly   455 FHTVPQ----GVHM 464
            .....:    .|||
  Rat   446 LRAENESGNVAVHM 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	55/167 (33%)
Arhgap15	NP_001013939.1	PH	88..197	CDD:278594
		PH_ARHGAP9-like	89..199	CDD:270053
		RhoGAP_ARHGAP27_15_12_9	286..472	CDD:239868	61/184 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000816
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000