DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP16F and rga7

DIOPT Version :9

Sequence 1:	NP_001285400.1	Gene:	RhoGAP16F / 32790	FlyBaseID:	FBgn0030893	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_595866.1	Gene:	rga7 / 2540635	PomBaseID:	SPBC23G7.08c	Length:	695	Species:	Schizosaccharomyces pombe

Alignment Length:	211	Identity:	54/211 - (25%)
Similarity:	99/211 - (46%)	Gaps:	27/211 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 FDTELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGIYRQCGDYNKIQTLRFSIDANDYD 353
            |...|:.::.. :|..:|.||:.|...:|    .....::||||......::..||...:.|...
pombe   504 FGARLDAIILR-EHSNIPNIVMQCTSQVE----NFGLNLQGIYRVPSSSARVNMLRSQFENNPLL 563

  Fly   354 SLRQP---DVDIHTLTGVLKLFLREIKSPLVRVNEAKTFIGQPNQWLLTDLSAKLDSLKRLIRSL 415
            .|..|   :.|:|.:..:||:|.||::.||:..|..:.||...|   :.|.|.:.|::.|.|..|
pombe   564 QLHTPEDYENDVHAVADLLKIFFRELREPLIPDNHQRDFIDAGN---VEDESRRRDAVHRAINDL 625

  Fly   416 PESNRDTMDYIFGHFNRITK-VPLQQISAETLSISVTPSIFH--TVPQGVHMQDIQQLLREGETL 477
            |::|..|:.::..|..:|.: ..:.::|...|:|...|:|..  |:|             |..:.
pombe   626 PDANYSTIRHLTIHLAKIKENSDVNKMSTNNLAIIWGPTIIKQATIP-------------EISSF 677

  Fly   478 ADCVKLMIEYQGRIFD 493
            :..::::|:|...|||
pombe   678 SRTIEILIDYCFTIFD 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP16F	NP_001285400.1	RhoGAP	306..487	CDD:238090	47/186 (25%)
rga7	NP_595866.1	F-BAR_Rgd1	39..277	CDD:153336
		PRR18	335..>406	CDD:292299
		RhoGAP_fRGD1	504..692	CDD:239863	51/208 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910