DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGAP16F and Arhgap31

DIOPT Version :10

Sequence 1:NP_001285400.1 Gene:RhoGAP16F / 32790 FlyBaseID:FBgn0030893 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_064656.2 Gene:Arhgap31 / 12549 MGIID:1333857 Length:1425 Species:Mus musculus


Alignment Length:315 Identity:66/315 - (20%)
Similarity:118/315 - (37%) Gaps:100/315 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   305 VPRIVVDCCDLIEQKYRRSTQPIEGIYRQCGDYNKIQTLRFSIDANDYDSLRQPDV-------DI 362
            ||.::..|.:.||     :...::||||..|..:.||.||     .::.|.:.||:       ||
Mouse    34 VPYVLKSCAEFIE-----THGIVDGIYRLSGITSNIQRLR-----QEFGSDQCPDLTREVYLQDI 88

  Fly   363 HTLTGVLKLFLREIKSPLV------RVNEAKTFIGQPNQWLLTDLSAKLDSLKRLIRSLPESNRD 421
            |.:..:.||:.||:.:||:      :..||.:.  :|.:       .:|..::.:|..||..:..
Mouse    89 HCVGSLCKLYFRELPNPLLTYELYEKFTEAVSH--RPEE-------GQLARIQNVILELPPPHYR 144

  Fly   422 TMDYIFGHFNRITKVPLQ-QISAETLSISVTPSIFH------TVPQG------VHMQDIQQLLRE 473
            |::|:..|...|.....: .:.|..|::...|::..      |:..|      |.:|.:      
Mouse   145 TLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQV------ 203

  Fly   474 GETLADCVKLMIEYQGRIF----------DRLRLIQTAHLLCRCVERFANHSKSEILNPKPNTPL 528
                  .::.::.:..:||          |..|.|                :||..| |..:.|:
Mouse   204 ------VIEFILNHADQIFNGGAPGALQQDESRTI----------------TKSLTL-PALSLPM 245

  Fly   529 YLPHL----------------YTHSRFAPESVSNPDHIVYRCTADRRRLSMRNLK 567
            .|..|                .......||.|..|.|.|.....::|:||.::.|
Mouse   246 KLVSLEEAQARSLATNHPARKERRENSLPEIVPPPFHTVLELPDNKRKLSSKSKK 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP16FNP_001285400.1 RhoGAP 306..487 CDD:238090 43/206 (21%)
Arhgap31NP_064656.2 RhoGAP_CdGAP 17..211 CDD:239849 44/207 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 258..277 2/18 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 511..621
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 652..700
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 756..951
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1031..1095
PHA03247 <1181..1302 CDD:223021
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1196..1260
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1291..1327
Blue background indicates that the domain is not in the aligned region.

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