DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and hdhA

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_416136.1	Gene:	hdhA / 946151	ECOCYCID:	EG10425	Length:	255	Species:	Escherichia coli

Alignment Length:	251	Identity:	75/251 - (29%)
Similarity:	128/251 - (50%)	Gaps:	24/251 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKE---LGDKVVFVPVDVTSEKDVSAA 68
            :::||..:|:|:..|...|..||||:::|:.:...|.|..|   ||.:......|:|||:::||.
E. coli    14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSAL 78

  Fly    69 LQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGAN 133
            ...|..|.|::|:.||.|| ....|.|:.      .:.||:|...:|....|::.:|.|..|..|
E. coli    79 ADFAISKLGKVDILVNNAG-GGGPKPFDM------PMADFRRAYELNVFSFFHLSQLVAPEMEKN 136

  Fly   134 EPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTP 198
                  ..|||:...|:||.:..|...:|::||||...:...:|.||..:.||:..||||...|.
E. coli   137 ------GGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTD 195

  Fly   199 MLAAL--PEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPL---LNGEVIRIDG 249
            .|.::  || :...:.:..|. :|||:|.:.|:....:. :|.   ::|:::.:.|
E. coli   196 ALKSVITPE-IEQKMLQHTPI-RRLGQPQDIANAALFLC-SPAASWVSGQILTVSG 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	75/251 (30%)
hdhA	NP_416136.1	PRK06113	1..255	CDD:135765	75/251 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	2	1.910