DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and HSD5

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_192740.1	Gene:	HSD5 / 826593	AraportID:	AT4G10020	Length:	389	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	67/247 - (27%)
Similarity:	109/247 - (44%)	Gaps:	36/247 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEV---AKELG-DKVVFVPVDVTSE 62
            :::.|.::||.:|.:|...|...||:||:::|......:...|   ||::| :.|:.:..||..|
plant    47 MEDKVVVITGASSAIGEQIAYEYAKRGANLVLVARREQRLRVVSNKAKQIGANHVIIIAADVIKE 111

  Fly    63 KDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLED---FQRVININTVGTFNVIR 124
            .|....:..|.:.:||:|..||   ||:...||.|.:     :.|   |..:::||..|  ||..
plant   112 DDCRRFITQAVNYYGRVDHLVN---TASLGHTFYFEE-----VSDTTVFPHLLDINFWG--NVYP 166

  Fly   125 LSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQ-GIRIC 188
            ....|...::.|     |.||..|||..:......:.|||:|||:|.....:..:|:.. ||.|.
plant   167 TYVALPYLHQTN-----GRIVVNASVENWLPLPRMSLYSAAKAALVNFYETLRFELNGDVGITIA 226

  Fly   189 T-------IAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQA 233
            |       ::.|.|      .|.|.......:....|...|...|:|.::.|
plant   227 THGWIGSEMSGGKF------MLEEGAEMQWKEEREVPANGGPLEEFAKMIVA 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	67/246 (27%)
HSD5	NP_192740.1	NADB_Rossmann	47..303	CDD:419666	67/247 (27%)
HSD5	NP_192740.1	Extensin_2	343..>379	CDD:252669
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910